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anti-MGA antibody :: Mouse anti-Human MGA Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120058
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MGA, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human MGA

 Product Synonym Names    MAX gene associated; KIAA0518; MAD5; MXD5; FLJ12634
 Product Gene Name   

anti-MGA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    616061
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    MGA6A4H5
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-MGA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MGA antibody   

Dot Blot (DB)

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 Quality Control of anti-MGA antibody    Western blot analysis of immunized recombinant protein, using anti-MGA monoclonal antibody.
anti-MGA antibody Quality Control image
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 Quality Control #2 of anti-MGA antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-MGA antibody Quality Control #2 image
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NCBI/Uniprot data below describe general gene information for MGA. It may not necessarily be applicable to this product.
 NCBI GI #    34192191
 NCBI GeneID    23269
 NCBI Accession #    BC038449 [Other Products]
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 UniProt Secondary Accession #    Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9; E7ENI0; F5H7K2 [Other Products]
 UniProt Related Accession #    Q8IWI9 [Other Products]
 Molecular Weight    336,159 Da
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 NCBI Official Full Name    Homo sapiens MAX gene associated, mRNA
 NCBI Official Synonym Full Names    MGA, MAX dimerization protein
 NCBI Official Symbol    MGA [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    MAX gene-associated protein; MAX dimerization protein 5
 UniProt Protein Name    MAX gene-associated protein
 UniProt Synonym Protein Names   
MAX dimerization protein 5
 Protein Family    MAX gene-associated protein
 UniProt Gene Name    MGA [Similar Products]
 UniProt Entry Name    MGAP_HUMAN
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 UniProt Comments for MGA    MGA iso6: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; DNA-binding

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm

Molecular Function: protein dimerization activity; DNA binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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 Research Articles on MGA    1. Results show that inactivation of MGA was observed in both non-small cell lung cancer and SCLC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-MGA antibodyOrgans/Tissues associated with anti-MGA antibody
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >20 publications with MGA and Kidney Diseases
 Weight Gain Antibodies  >17 publications with MGA and Weight Gain
 Adenocarcinoma Antibodies  >16 publications with MGA and Adenocarcinoma
 Congenital Abnormalities Antibodies  >15 publications with MGA and Congenital Abnormalities
 Neoplasm Metastasis Antibodies  >9 publications with MGA and Neoplasm Metastasis
 Proteinuria Antibodies  >9 publications with MGA and Proteinuria
 Inflammation Antibodies  >8 publications with MGA and Inflammation
 Necrosis Antibodies  >7 publications with MGA and Necrosis
 Hypertrophy Antibodies  >7 publications with MGA and Hypertrophy
 Hyperplasia Antibodies  >6 publications with MGA and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >45 publications with MGA and Muscle
 Brain Antibodies  >38 publications with MGA and Brain
 Nerve Antibodies  >33 publications with MGA and Nerve
 Ovary Antibodies  >31 publications with MGA and Ovary
 Kidney Antibodies  >28 publications with MGA and Kidney
 Liver Antibodies  >27 publications with MGA and Liver
 Skin Antibodies  >20 publications with MGA and Skin
 Lung Antibodies  >15 publications with MGA and Lung
 Uterus Antibodies  >13 publications with MGA and Uterus
 Heart Antibodies  >12 publications with MGA and Heart
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