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anti-MIS12 antibody :: Mouse MIS12 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS831246
Western Blot (WB)
Unit / Price
0.05 mg  /  $275 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MIS12, Monoclonal Antibody

 Also Known As   

MIS12 antibody

 Product Synonym Names    Monoclonal MIS12; Anti-MIS12; MIS12; KNTC2AP; MGC2488; MIS-12; MIS 12; 2510025F08Rik; hMis12; MIND kinetochore complex component homolog; MTW1
 Product Gene Name   

anti-MIS12 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609178
 3D Structure    ModBase 3D Structure for Q9H081
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2572C2a
 Host    Mouse
 Species Reactivity    Human. Other species not studied
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 Specificity    Human MIS12
 Purity/Purification    MIS12 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Form/Format    MIS12 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4, 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3).
 Concentration    100 ug/ml (lot specific)
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 Biological Significance    This gene forms part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis.
 Biohazard Information    This antibody solution contains sodium azide (NaN) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice.
 Immunogen    MIS12 antibody was raised in mouse using recombinant Human Mis12, Mind Kinetochore Complex Component, Homolog (S.Pombe) (Mis12)
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 Preparation and Storage    Store at 2-8 degree C for up to one year. We recommend long term storage at -20 degree C. Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-MIS12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MIS12 antibody

   Mouse monoclonal MIS12 antibody
 Product Categories/Family for anti-MIS12 antibody    DNA & RNA
 Applications Tested/Suitable for anti-MIS12 antibody   

Dot Blot (DB)

 Application Notes for anti-MIS12 antibody    To be optimized by the end user.
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 Western Blot (WB) of anti-MIS12 antibody   
anti-MIS12 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MIS12. It may not necessarily be applicable to this product.
 NCBI GI #    49065346
 NCBI GeneID    79003
 NCBI Accession #    CAG38491.1 [Other Products]
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 UniProt Primary Accession #    Q9H081 [Other Products]
 UniProt Secondary Accession #    Q96N24 [Other Products]
 UniProt Related Accession #    Q9H081 [Other Products]
 Molecular Weight    24,140 Da
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 NCBI Official Full Name    MIS12
 NCBI Official Synonym Full Names    MIS12 kinetochore complex component
 NCBI Official Symbol    MIS12 [Similar Products]
 NCBI Official Synonym Symbols   
MTW1; hMis12; KNTC2AP; 2510025F08Rik
[Similar Products]
 NCBI Protein Information    protein MIS12 homolog
 UniProt Protein Name    Protein MIS12 homolog
 Protein Family    Protein
 UniProt Gene Name    MIS12 [Similar Products]
 UniProt Entry Name    MIS12_HUMAN
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 UniProt Comments for MIS12    MIS12: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Belongs to the mis12 family.

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: nucleus; cytosol; MIS12/MIND type complex

Molecular Function: protein binding

Biological Process: mitosis; kinetochore assembly; cell division; mitotic cell cycle; chromosome segregation
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 Research Articles on MIS12    1. Mechanisms of mitosis-specific assembly of the checkpoint platform Knl1/MIS12/NDC80 at human kinetochores.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MIS12 antibodyPathways associated with anti-MIS12 antibody
 Reference Product  PubMed Publications
 NDC80 antibody  >44 publications with MIS12 and NDC80
 CASC5 antibody  >10 publications with MIS12 and CASC5
 NUF2 antibody  >9 publications with MIS12 and NUF2
 DSN1 antibody  >8 publications with MIS12 and DSN1
 BUB1 antibody  >7 publications with MIS12 and BUB1
 ZWINT antibody  >7 publications with MIS12 and ZWINT
 SPC24 antibody  >5 publications with MIS12 and SPC24
 NSL1 antibody  >3 publications with MIS12 and NSL1
 PMF1 antibody  >1 publications with MIS12 and PMF1
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic Anaphase Pathway antibodies  Mitotic Anaphase Pathway Diagram
 Mitotic Metaphase And Anaphase Pathway antibodies  Mitotic Metaphase And Anaphase Pathway Diagram
 Mitotic Prometaphase Pathway antibodies  Mitotic Prometaphase Pathway Diagram
 RHO GTPase Effectors Pathway antibodies  RHO GTPase Effectors Pathway Diagram
 RHO GTPases Activate Formins Pathway antibodies  RHO GTPases Activate Formins Pathway Diagram
 Resolution Of Sister Chromatid Cohesion Pathway antibodies  Resolution Of Sister Chromatid Cohesion Pathway Diagram
 Separation Of Sister Chromatids Pathway antibodies  Separation Of Sister Chromatids Pathway Diagram
Diseases associated with anti-MIS12 antibodyOrgans/Tissues associated with anti-MIS12 antibody
 Disease Name  Pubmed Publications
 Craniofacial Abnormalities Antibodies  >1 publications with MIS12 and Craniofacial Abnormalities
 Nervous System Diseases Antibodies  >1 publications with MIS12 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with MIS12 and Nerve
 Blood Antibodies  >1 publications with MIS12 and Blood
 Brain Antibodies  >1 publications with MIS12 and Brain
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