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anti-Mmp-1 antibody :: Mouse anti-Human MMP-1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS670147 anti-Mmp-1 antibody
Unit / Price
0.1 mg  /  $265 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MMP-1, Monoclonal Antibody

 Also Known As   

Mouse Anti-Human MMP-1-UNLB

 Product Synonym Names    Mouse Anti-Human MMP-1 - Purified, Unlabeled Antibody; Mouse Anti-Human MMP-1
 Product Gene Name   

anti-Mmp-1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_007420.2 (9999663..10008814)
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 Clonality    Monoclonal
 Isotype    Mouse IgG2b
 Clone Number    SB12e
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Human MMP-1; Does not cross react to human MMP-2, MMP-3 or MMP-9
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase, and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, alpha 1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1 beta, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs.1-15
 Form/Format    Purified (UNLB) Antibody
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 Immunogen    Recombinant MMP-1
 Characterization    To insure lot-to-lot consistency, each batch of product is tested by ELISA to conform with the characteristics of a standard reference reagent.
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 Preparation and Storage    The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C.
The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20 degree C.
The biotin (BIOT) conjugate is supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store at 2-8 degree C.
Reagents are stable for the period shown on the label if stored as directed.
 Other Notes    Small volumes of anti-Mmp-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Mmp-1 antibody   

ELISA; Immunohistochemistry_PES; Western Blot

 Application Notes for anti-Mmp-1 antibody    Immunohistochemistry Suggested Dilution: <= 2 ug/mL
ELISA Suggested Dilution: 1:3,000-1:8,000
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NCBI/Uniprot data below describe general gene information for Mmp-1. It may not necessarily be applicable to this product.
 NCBI GI #    255958234
 NCBI GeneID    657261
 NCBI Accession #    NP_001157647.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164175.1 [Other Products]
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 NCBI Official Full Name    matrix metalloproteinase 1 isoform 2
 NCBI Official Symbol    Mmp-1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    matrix metalloproteinase 1; GLEAN_14266
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Product References and Citations for anti-Mmp-1 antibody

   1. Welgus, H.G., C.J. Fliszar, J.L. Seltzer, T.M. Schmid, and J.J. Jeffery. 1990. J. Biol. Chem. 265:13521.
2. Fosang, A.J., K. Last, V. Knauper, P.J. Neame, G. Murphy, T.E. Hardingham, H. Tschesche, and J.A. Hamilton. 1993. Biochem. J. 295:273.
3. Perides, G., R.A. Asher, M.W. Lark, W.S. Lane, R.A. Robinson, and A. Bignami. 1995. Biochem. J. 312:377.
4. Nguyen, Q., G. Murphy, C.E. Hughes, J.S. Mort, and P.J. Roughley. 1993. Biochem. J. 295:595.
5. Imai, K., M. Kusakabe, T. Sakakura, I. Nakanishi, and Y. Okada. 1994. FEBS Letters 352:216.
6. Sires, U.I., G. Murphy, V.M. Baragi, C.J. Fliszar, H.G. Welhus, and R.M. Senior. 1994. Biochem. Biophys. Res. Comm. 204:613.
7. Desrochers, P.E., J.J. Jeffery, and S.J. Weiss. 1991. J. Clin. Invest. 87:2258.
8. Mast. A.E., J.J. Enghild, H. Nagase, K. Suzuki, S.V. Pizzo, and G. Salvesen. 1991. J. Biol. Chem. 266:15810.
9. Sires, U.I., G.L. Griffin, T.J. Broekelmann, R.P. Mecham, G. Murphy, A.E. Ching, H.G. Welhus, and R.M. Senior. 1993. J. Biol. Chem. 268:2069.
10. Preece, G., G. Murphy, and A. Ager. 1996. J. Biol. Chem. 271:11634.
11. Ito, A., A. Mukaiyama, Y. Itoh, H. Magase, I.B. Thogersen, J.J. Enghild, Y. Sasaguri, and Y. Mori. 1996. J. Biol. Chem. 271:14657.
12. Fowlkes, J.L., J.J. Enghild, K. Suzuki, and H. Nagase. 1994. J. Biol. Chem. 269:25742.
13. Chandler, S., R. Coates, A. Gearing, J. Lury, G. Wells, and E. Bone. 1995. Neurosci. Lett. 201:223.
14. Thrailkill, K.M., L.D. Quarles, H. Nagase, K. Suzuki, D.M. Serra, and J.L. Fowlkes. 1995. Endocrinology 136:3527.
15. Crabbe, T., J.P. O'Connell, B.J. Smith, and A.J. Docherty. 1994. Biochemistry 33:11419.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-Mmp-1 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Mmp-1 and Bone
 Connective Tissue Antibodies  >4 publications with Mmp-1 and Connective Tissue
 Heart Antibodies  >3 publications with Mmp-1 and Heart
 Muscle Antibodies  >3 publications with Mmp-1 and Muscle
 Brain Antibodies  >3 publications with Mmp-1 and Brain
 Vascular Antibodies  >2 publications with Mmp-1 and Vascular
 Embryonic Tissue Antibodies  >2 publications with Mmp-1 and Embryonic Tissue
 Ear Antibodies  >1 publications with Mmp-1 and Ear
 Kidney Antibodies  >1 publications with Mmp-1 and Kidney
 Umbilical Cord Antibodies  >1 publications with Mmp-1 and Umbilical Cord
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