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anti-MUCIN 2 antibody :: Mouse MUCIN 2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS216981 anti-MUCIN 2 antibody
Unit / Price
0.1 mg  /  $375 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MUCIN 2, Monoclonal Antibody

★Popular Item★
 Also Known As   

MOUSE ANTI HUMAN MUCIN 2:FITC

 Product Synonym Names    MUC-2, SMUC
 Product Gene Name   

anti-MUCIN 2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    158370
 3D Structure    ModBase 3D Structure for Q02817
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    996/1
 Host    Mouse
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 Specificity    Mouse anti Human Muccin 2 Antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In formalin fixed, paraffin embedded tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa.
 Form/Format    FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
 Concentration    IgG concentration 0.1 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
 Preparation    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
 Immunogen    MUC-2 tandem repeat peptide.
 Buffer Solution    Phosphate buffered saline
 Target Species    Human
 Fusion Partners    Spleen cells from immunised Balb/c mice were fused with cells of a mouse NS0 myeloma cell line.
 Max Ex/Em    Fluorophore: FITC
Excitation (nm): 490
Emission (nm): 520
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 Preparation and Storage    Store at 4C or -20C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-MUCIN 2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MUCIN 2 antibody

   Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa.
 Applications Tested/Suitable for anti-MUCIN 2 antibody   

Flow cytometry

 Application Notes for anti-MUCIN 2 antibody    Suggested Dilution: Neat-1/10

Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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NCBI/Uniprot data below describe general gene information for MUCIN 2. It may not necessarily be applicable to this product.
 NCBI GI #    557129045
 NCBI GeneID    4583
 NCBI Accession #    NP_002448.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_002457.3 [Other Products]
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 UniProt Primary Accession #    Q02817 [Other Products]
 UniProt Secondary Accession #    Q14878 [Other Products]
 UniProt Related Accession #    Q02817 [Other Products]
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 NCBI Official Full Name    mucin-2
 NCBI Official Synonym Full Names    mucin 2, oligomeric mucus/gel-forming
 NCBI Official Symbol    MUC2 [Similar Products]
 NCBI Official Synonym Symbols   
MLP; SMUC; MUC-2
[Similar Products]
 NCBI Protein Information    mucin-2; intestinal mucin-2; mucin 2, intestinal/tracheal; mucin-like protein
 UniProt Protein Name    Mucin-2
 UniProt Synonym Protein Names   
Intestinal mucin-2
 UniProt Gene Name    MUC2 [Similar Products]
 UniProt Synonym Gene Names    SMUC; MUC-2 [Similar Products]
 UniProt Entry Name    MUC2_HUMAN
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 NCBI Summary for MUCIN 2    This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MUCIN 2    MUC2: Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

Protein type: Secreted; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: Golgi lumen

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; maintenance of gastrointestinal epithelium; post-translational protein modification
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 Research Articles on MUCIN 2    1. There was no difference in the expression of deep MUC1, MUC2, MUC5AC, or MUC6 between the groups of gastric cancer and controls.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MUCIN 2 antibodyPathways associated with anti-MUCIN 2 antibody
 Reference Product  PubMed Publications
 MUC1 antibody  >561 publications with MUCIN 2 and MUC1
 MUC4 antibody  >209 publications with MUCIN 2 and MUC4
 MUC7 antibody  >67 publications with MUCIN 2 and MUC7
 MUC17 antibody  >13 publications with MUCIN 2 and MUC17
 MUC3A antibody  >10 publications with MUCIN 2 and MUC3A
 MUC15 antibody  >7 publications with MUCIN 2 and MUC15
 MUC12 antibody  >7 publications with MUCIN 2 and MUC12
 MUC20 antibody  >6 publications with MUCIN 2 and MUC20
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Termination Of O-glycan Biosynthesis Pathway antibodies  Termination Of O-glycan Biosynthesis Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
Diseases associated with anti-MUCIN 2 antibodyOrgans/Tissues associated with anti-MUCIN 2 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >583 publications with MUCIN 2 and Adenocarcinoma
 Intestinal Neoplasms Antibodies  >547 publications with MUCIN 2 and Intestinal Neoplasms
 Pancreatic Neoplasms Antibodies  >168 publications with MUCIN 2 and Pancreatic Neoplasms
 Adenoma Antibodies  >153 publications with MUCIN 2 and Adenoma
 Inflammation Antibodies  >138 publications with MUCIN 2 and Inflammation
 Neoplasm Metastasis Antibodies  >98 publications with MUCIN 2 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >68 publications with MUCIN 2 and Liver Neoplasms
 Precancerous Conditions Antibodies  >68 publications with MUCIN 2 and Precancerous Conditions
 Hyperplasia Antibodies  >64 publications with MUCIN 2 and Hyperplasia
 Necrosis Antibodies  >60 publications with MUCIN 2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >553 publications with MUCIN 2 and Intestine
 Stomach Antibodies  >320 publications with MUCIN 2 and Stomach
 Blood Antibodies  >90 publications with MUCIN 2 and Blood
 Muscle Antibodies  >53 publications with MUCIN 2 and Muscle
 Kidney Antibodies  >25 publications with MUCIN 2 and Kidney
 Thyroid Antibodies  >16 publications with MUCIN 2 and Thyroid
 Ascites Antibodies  >10 publications with MUCIN 2 and Ascites
 Brain Antibodies  >8 publications with MUCIN 2 and Brain
 Placenta Antibodies  >2 publications with MUCIN 2 and Placenta
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