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anti-MYL4 antibody :: Mouse anti-Human MYL4 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS200272
Western Blot (WB)
Unit / Price
0.05 mL  /  $240 +1 FREE 8GB USB
0.1 mL  /  $315 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MYL4, Monoclonal Antibody

★Popular Item★
 Also Known As   

MYL4 antibody

 Product Synonym Names    Myosin light chain 4; Myosin; light chain 4; ALC1; AMLC; GT1
 Product Gene Name   

anti-MYL4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M36172 mRNA
 3D Structure    ModBase 3D Structure for P12829
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 Clonality    Monoclonal
 Isotype    IgG2a,k
 Clone Number    AT4E8
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    By protein-A affinity chromatography
 Form/Format    Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
 Concentration    1mg/ml (lot specific)
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 Antigen Species    Human
 Immunogen    Recombinant human MYL4 (1-197aa) purified from E. coli
 Clone Note    Anti-human MYL4 mAb, clone AT4E8, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MYL4 protein.
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 Preparation and Storage    Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of anti-MYL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MYL4 antibody

   Myosin light chain 4 is a protein that in humans is encoded by the MYL4 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
 Product Categories/Family for anti-MYL4 antibody    Cytoskeleton
 Applications Tested/Suitable for anti-MYL4 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-MYL4 antibody    Recommended starting dilution is 1:1000.
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 Western Blot (WB) of anti-MYL4 antibody    The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MYL4 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MYL4 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: HepG2 cell lysate Lane 2.: K562 cell lysate Lane 3.: MCF7 cell lysate Lane 4.: Jurkat cell lysate Lane 5.: 293T cell lysate Lane 6.: LnCap cell lysate
anti-MYL4 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MYL4. It may not necessarily be applicable to this product.
 NCBI GI #    50845428
 NCBI GeneID    4635
 NCBI Accession #    NP_001002841 [Other Products]
 NCBI GenBank Nucleotide #    NM_001002841.1 [Other Products]
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 UniProt Primary Accession #    P12829 [Other Products]
 UniProt Secondary Accession #    P11783; D3DXJ7 [Other Products]
 UniProt Related Accession #    P12829 [Other Products]
 Molecular Weight    21,565 Da
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 NCBI Official Full Name    myosin light chain 4
 NCBI Official Synonym Full Names    myosin light chain 4
 NCBI Official Symbol    MYL4 [Similar Products]
 NCBI Official Synonym Symbols   
GT1; ALC1; AMLC; PRO1957
[Similar Products]
 NCBI Protein Information    myosin light chain 4
 UniProt Protein Name    Myosin light chain 4
 UniProt Synonym Protein Names   
Myosin light chain 1, embryonic muscle/atrial isoform; Myosin light chain alkali GT-1 isoform
 Protein Family    Myosin
 UniProt Gene Name    MYL4 [Similar Products]
 UniProt Synonym Gene Names    MLC1 [Similar Products]
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 NCBI Summary for MYL4    Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MYL4    Regulatory light chain of myosin. Does not bind calcium.
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Product References and Citations for anti-MYL4 antibody

   Kurabayashi, M., et al. (1998) J Biol Chem 263 (27): 13930-6; Rotter, M., et al. (1991) Nucleic Acids Res 19 (7): 1497-504;
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 Research Articles on MYL4    1. a novel, heterozygous p.Glu11Lys mutation in the atrial-specific myosin light chain gene MYL4, caused atrial fibrillation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MYL4 antibodyPathways associated with anti-MYL4 antibody
 Reference Product  PubMed Publications
 MYH3 antibody  >2 publications with MYL4 and MYH3
 TNNT2 antibody  >1 publications with MYL4 and TNNT2
 MYL2 antibody  >1 publications with MYL4 and MYL2
 MYH8 antibody  >1 publications with MYL4 and MYH8
 MYH6 antibody  >1 publications with MYL4 and MYH6
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Apelin Signaling Pathway antibodies  Apelin Signaling Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
Diseases associated with anti-MYL4 antibodyOrgans/Tissues associated with anti-MYL4 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5 publications with MYL4 and Cardiovascular Diseases
 Heart Diseases Antibodies  >5 publications with MYL4 and Heart Diseases
 Congenital Abnormalities Antibodies  >2 publications with MYL4 and Congenital Abnormalities
 Fibrosis Antibodies  >2 publications with MYL4 and Fibrosis
 Liver Diseases Antibodies  >1 publications with MYL4 and Liver Diseases
 Vascular Diseases Antibodies  >1 publications with MYL4 and Vascular Diseases
 ATRIAL FIBRILLATION, FAMILIAL, 18 Antibodies  >1 publications with MYL4 and ATRIAL FIBRILLATION, FAMILIAL, 18
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >12 publications with MYL4 and Muscle
 Heart Antibodies  >8 publications with MYL4 and Heart
 Blood Antibodies  >4 publications with MYL4 and Blood
 Embryonic Tissue Antibodies  >2 publications with MYL4 and Embryonic Tissue
 Eye Antibodies  >1 publications with MYL4 and Eye
 Lung Antibodies  >1 publications with MYL4 and Lung
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