Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow SERPINB5 rightarrow Monoclonal SERPINB5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Lysosomal Associated Membrane Protein 1 (LAMP1) ELISA Kit
 • Phosphatidylcholine Antibody (IgA) ELISA Kit
 • enolase 2 (gamma, neuronal) (ENO2) ELISA Kit
 • PRICKLE1 Antibody
 • 15-F2t-Isoprostane purified IgG Antibody
 • Defensin Alpha 5, Paneth Cell Specific (DEFa5) ELISA Kit
 • Angiopoietin-2 - Ang-2 Recombinant Protein
 • Unconventional myosin-VIIa (Myo7a) Recombinant Protein
 • 14-3-3 zeta Antibody
 • Relaxin (RLT) ELISA Kit
 • Cardiac myosin light chains 1 (CMIC 1) ELISA Kit
 • Orexin receptor type 1 (HCRTR1) Recombinant Protein
 • Glutaredoxin-1 (GLRX) ELISA Kit
 • CD68 molecule ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-SERPINB5 antibody :: Mouse anti-Human Maspin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS200148
Unit / Price
0.05 mL  /  $240 +1 FREE 8GB USB
0.1 mL  /  $315 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Maspin (SERPINB5), Monoclonal Antibody

 Also Known As   

Maspin antibody

 Product Synonym Names    Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serpin B5; Protease inhibitor 5; SERPINB5; PI5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor; clade B; member 5; Ovalbumin; PI-5; Serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; Spi5; Spi7.
 Product Gene Name   

anti-SERPINB5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    U04313 mRNA
 3D Structure    ModBase 3D Structure for P36952
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2b, k
 Clone Number    AT2N6
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Purity/Purification    By protein-G affinity chromatography
 Form/Format    Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
 Concentration    1mg/ml (lot specific)
Section Bar
 Antigen Species    Human
 Immunogen    Recombinant Maspin (1-375aa) purified from E. coli
 Clone Note    Anti-human Maspin mAb, clone AT2N6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Maspin protein.
Section Bar
 Preparation and Storage    Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of anti-SERPINB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-SERPINB5 antibody

   Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas.
 Product Categories/Family for anti-SERPINB5 antibody    Development
 Applications Tested/Suitable for anti-SERPINB5 antibody   

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

 Application Notes for anti-SERPINB5 antibody    WB: 1:1000 ~ 2000.
Recommended starting dilution is 1:1000.
Section Bar
 Western Blot (WB) of anti-SERPINB5 antibody    The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Maspin antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: HeLa cell lysate
anti-SERPINB5 antibody Western Blot (WB) (WB) image
Section Bar
 Immunofluorescence (IF) of anti-SERPINB5 antibody    Immunofluorescence of human HeLa cells stained with PI (Red) and monoclonal anti-Maspin antibody (1:500) with Alexa 488 (Green). ICC/IF analysis of Maspin in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Maspin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
anti-SERPINB5 antibody Immunofluorescence (IF) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for SERPINB5. It may not necessarily be applicable to this product.
 NCBI GI #    167860126
 NCBI GeneID    5268
 NCBI Accession #    NP_002630 [Other Products]
 NCBI GenBank Nucleotide #    NM_002639.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P36952 [Other Products]
 UniProt Secondary Accession #    Q6N0B4; Q8WW89; B2R6Y4 [Other Products]
 UniProt Related Accession #    P36952 [Other Products]
 Molecular Weight    25,763 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    serpin B5
 NCBI Official Synonym Full Names    serpin family B member 5
 NCBI Official Symbol    SERPINB5 [Similar Products]
 NCBI Official Synonym Symbols   
PI5; maspin
[Similar Products]
 NCBI Protein Information    serpin B5
 UniProt Protein Name    Serpin B5
 UniProt Synonym Protein Names   
Maspin; Peptidase inhibitor 5; PI-5
 Protein Family    Serpin
 UniProt Gene Name    SERPINB5 [Similar Products]
 UniProt Synonym Gene Names    PI5; PI-5 [Similar Products]
Section Bar
 UniProt Comments for SERPINB5    Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Table BarTOPTable Bar
 

Product References and Citations for anti-SERPINB5 antibody

   Lockett J. et al., (2006) J Cell Biochem 97 (4):651-660; Khalkhali Ellis Z. et al., (2006) Clin Cancer Res 12 (24):7279-7283
Section Bar
 Research Articles on SERPINB5    1. Study results provide new insights into the molecular mechanisms of maspin suppression in response to HBx, and revealed nuclear IKKalpha as a prognostic biomarker and a potential therapeutic target to improve the clinical outcome of HBV-associated HCC patients.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-SERPINB5 antibodyPathways associated with anti-SERPINB5 antibody
 Reference Product  PubMed Publications
 TP53 antibody  >4 publications with SERPINB5 and TP53
 PLAU antibody  >3 publications with SERPINB5 and PLAU
 IL6 antibody  >1 publications with SERPINB5 and IL6
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
Diseases associated with anti-SERPINB5 antibodyOrgans/Tissues associated with anti-SERPINB5 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >18 publications with SERPINB5 and Carcinoma
 Breast Neoplasms Antibodies  >16 publications with SERPINB5 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >13 publications with SERPINB5 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >10 publications with SERPINB5 and Adenocarcinoma
 Inflammation Antibodies  >8 publications with SERPINB5 and Inflammation
 Neoplasm Invasiveness Antibodies  >8 publications with SERPINB5 and Neoplasm Invasiveness
 Neoplasms, Experimental Antibodies  >7 publications with SERPINB5 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >6 publications with SERPINB5 and Lung Neoplasms
 Colorectal Neoplasms Antibodies  >5 publications with SERPINB5 and Colorectal Neoplasms
 Pancreatic Neoplasms Antibodies  >5 publications with SERPINB5 and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >6 publications with SERPINB5 and Prostate
 Bone Antibodies  >5 publications with SERPINB5 and Bone
 Intestine Antibodies  >4 publications with SERPINB5 and Intestine
 Muscle Antibodies  >3 publications with SERPINB5 and Muscle
 Stomach Antibodies  >3 publications with SERPINB5 and Stomach
 Pancreas Antibodies  >3 publications with SERPINB5 and Pancreas
 Heart Antibodies  >2 publications with SERPINB5 and Heart
 Uterus Antibodies  >2 publications with SERPINB5 and Uterus
 Bladder Antibodies  >2 publications with SERPINB5 and Bladder
 Liver Antibodies  >2 publications with SERPINB5 and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions