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anti-MMP9 antibody :: Mouse Matrix Metalloproteinase 9 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2025637 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $90 +1 FREE 8GB USB
0.02 mg  /  $100 +1 FREE 8GB USB
0.05 mg  /  $130 +1 FREE 8GB USB
0.1 mg  /  $160 +1 FREE 8GB USB
0.2 mg  /  $200 +1 FREE 8GB USB
1 mg  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Matrix Metalloproteinase 9 (MMP9), Monoclonal Antibody

★Popular Item★
 Also Known As   

Monoclonal Antibody to Matrix Metalloproteinase 9 (MMP9)

 Product Gene Name   

anti-MMP9 antibody

[Similar Products]
 Matching Pairs    Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
Antigen: Matrix Metalloproteinase 9 (MMP9) (MBS2012458)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
APC-CY7 Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043926)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
PE Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043928)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
APC-CY7 Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043930)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
Cy3 Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043932)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
FITC Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043933)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
HRP Conjugated Antibody: Matrix Metalloproteinase 9 (MMP9) (MBS2043935)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
 Matching Pairs    Unconjugated Antibody: Matrix Metalloproteinase 9 Clone #16# (MBS2025637)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2025637 Technical Datasheet    Technical Datasheet PDF
 OMIM    J05070 mRNA
 3D Structure    ModBase 3D Structure for P14780
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 Clonality    Monoclonal
 Isotype    IgG2b Kappa
 Clone Number    16#
 Host    Mouse
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 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    1 mg/ml (lot specific)
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 Organism Species    Homo sapiens (Human)
 Source    Monoclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant MMP9 (Gly213~Ala399) expressed in E.coli
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4║C for frequent use.
Aliquot and store at -20║C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37░C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-MMP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MMP9 antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-MMP9 antibody   

WB; IHC; ICC; IP.

 Application Notes for anti-MMP9 antibody    Western blotting: 0.5-5 ug/mL;1:200-2000
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200

Optimal working dilutions must be determined by end user.
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 Immunohistochemistry(IHC) of anti-MMP9 antibody    DAB staining on IHC6P; Samples
Human Breast cancer Tissue; Primary
Ab: 10 ug/ml Mouse Anti6Human MMP9
Antibody Second Ab: 2 ug/mL HRP6
Linked Caprine Anti-Mouse IgG
Polyclonal Antibody
(Catalog: MBS2086035)
anti-MMP9 antibody Immunohistochemistry(IHC) (IHC) image
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 Western Blot (WB) of anti-MMP9 antibody    Western Blot; Sample: Human U937 cell lysate; Primary Ab: 3ug/ml Mouse Anti-Human MMP9 Antibody Second Ab: 0.2ug/mLáHRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
anti-MMP9 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-MMP9 antibody    Western Blot; Sample: Recombinant MMP9, Human.
anti-MMP9 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MMP9. It may not necessarily be applicable to this product.
 NCBI GI #    74272287
 NCBI GeneID    4318
 NCBI Accession #    NP_004985.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004994.2 [Other Products]
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 UniProt Primary Accession #    P14780 [Other Products]
 UniProt Secondary Accession #    Q3LR70; Q8N725; Q9H4Z1; Q9UCJ9; Q9UCL1; Q9UDK2; B2R7V9 [Other Products]
 UniProt Related Accession #    P14780 [Other Products]
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 NCBI Official Full Name    matrix metalloproteinase-9 preproprotein
 NCBI Official Synonym Full Names    matrix metallopeptidase 9
 NCBI Official Symbol    MMP9 [Similar Products]
 NCBI Official Synonym Symbols   
GELB; CLG4B; MMP-9; MANDP2
[Similar Products]
 NCBI Protein Information    matrix metalloproteinase-9
 UniProt Protein Name    Matrix metalloproteinase-9
 UniProt Synonym Protein Names   
92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
 Protein Family    Matrix metalloproteinase
 UniProt Gene Name    MMP9 [Similar Products]
 UniProt Synonym Gene Names    CLG4B; MMP-9; GELB [Similar Products]
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 NCBI Summary for MMP9    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MMP9    MMP9: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. Activated by 4-aminophenylmercuric acetate and phorbol ester. Up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. Produced by normal alveolar macrophages and granulocytes. Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. Belongs to the peptidase M10A family.

Protein type: EC 3.4.24.35; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; proteinaceous extracellular matrix; tertiary granule lumen

Molecular Function: collagen binding; endopeptidase activity; identical protein binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; serine-type endopeptidase activity; zinc ion binding

Biological Process: cellular response to cadmium ion; cellular response to reactive oxygen species; collagen catabolic process; embryo implantation; endodermal cell differentiation; ephrin receptor signaling pathway; extracellular matrix disassembly; leukocyte migration; macrophage differentiation; negative regulation of apoptosis; negative regulation of cation channel activity; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; negative regulation of intrinsic apoptotic signaling pathway; neutrophil degranulation; ossification; positive regulation of cell migration; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of keratinocyte migration; positive regulation of protein phosphorylation; positive regulation of receptor binding; positive regulation of release of cytochrome c from mitochondria; positive regulation of vascular smooth muscle cell proliferation; proteolysis; skeletal system development

Disease: Metaphyseal Anadysplasia 2
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 Research Articles on MMP9    1. Review/Meta-analysis: MMP-9 rs3918242 variants (T allele, TT and CT genotypes) contributed to significantly increase the risk of ischemic stroke in the Chinese population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MMP9 antibodyPathways associated with anti-MMP9 antibody
 Reference Product  PubMed Publications
 MMP7 antibody  >59 publications with MMP9 and MMP7
 TIMP3 antibody  >52 publications with MMP9 and TIMP3
 IL8 antibody  >30 publications with MMP9 and IL8
 MMP10 antibody  >26 publications with MMP9 and MMP10
 CD44 antibody  >22 publications with MMP9 and CD44
 COL1A1 antibody  >18 publications with MMP9 and COL1A1
 CXCL1 antibody  >14 publications with MMP9 and CXCL1
 THBS1 antibody  >13 publications with MMP9 and THBS1
 RECK antibody  >13 publications with MMP9 and RECK
 CXCL5 antibody  >9 publications with MMP9 and CXCL5
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of Collagen Pathway antibodies  Degradation Of Collagen Pathway Diagram
 Degradation Of Collagen Pathway antibodies  Degradation Of Collagen Pathway Diagram
Diseases associated with anti-MMP9 antibodyOrgans/Tissues associated with anti-MMP9 antibody
 Disease Name  Pubmed Publications
 Neoplasm Invasiveness Antibodies  >213 publications with MMP9 and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >200 publications with MMP9 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >98 publications with MMP9 and Breast Neoplasms
 Liver Diseases Antibodies  >91 publications with MMP9 and Liver Diseases
 Aortic Diseases Antibodies  >68 publications with MMP9 and Aortic Diseases
 Aortic Aneurysm Antibodies  >60 publications with MMP9 and Aortic Aneurysm
 Brain Ischemia Antibodies  >52 publications with MMP9 and Brain Ischemia
 Aortic Aneurysm, Abdominal Antibodies  >51 publications with MMP9 and Aortic Aneurysm, Abdominal
 Carcinoma, Squamous Cell Antibodies  >49 publications with MMP9 and Carcinoma, Squamous Cell
 Myocardial Infarction Antibodies  >42 publications with MMP9 and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >527 publications with MMP9 and Blood
 Lung Antibodies  >236 publications with MMP9 and Lung
 Bone Antibodies  >232 publications with MMP9 and Bone
 Brain Antibodies  >171 publications with MMP9 and Brain
 Liver Antibodies  >135 publications with MMP9 and Liver
 Bone Marrow Antibodies  >102 publications with MMP9 and Bone Marrow
 Connective Tissue Antibodies  >88 publications with MMP9 and Connective Tissue
 Kidney Antibodies  >86 publications with MMP9 and Kidney
 Embryonic Tissue Antibodies  >74 publications with MMP9 and Embryonic Tissue
 Lymph Node Antibodies  >67 publications with MMP9 and Lymph Node
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