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anti-MPO antibody :: Mouse anti-Human Myeloperoxidase (MPO) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2044809 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-MPO antibody
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $165 +1 FREE 8GB USB
0.1 mg  /  $205 +1 FREE 8GB USB
0.2 mg  /  $265 +1 FREE 8GB USB
1 mg  /  $630 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myeloperoxidase (MPO), Monoclonal Antibody

 Also Known As   

APC-Linked Monoclonal Antibody to Myeloperoxidase (MPO)

 Product Gene Name   

anti-MPO antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    J02694 mRNA
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 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Human
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 Concentration    500ug/ml (lot specific)
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 Immunogen    Val165~Gly278
 Conjugation    APC
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2012608
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 Other Notes    Small volumes of anti-MPO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MPO antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for MPO. It may not necessarily be applicable to this product.
 NCBI GI #    188658
 NCBI GeneID    4353
 NCBI Accession #    AAA59863.1 [Other Products]
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 UniProt Secondary Accession #    Q14862; Q4PJH5; Q9UCL7; A1L4B8 [Other Products]
 UniProt Related Accession #    P05164 [Other Products]
 Molecular Weight    87,248 Da
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 NCBI Official Full Name    myeloperoxidase
 NCBI Official Synonym Full Names    myeloperoxidase
 NCBI Official Symbol    MPO [Similar Products]
 NCBI Protein Information    myeloperoxidase
 UniProt Protein Name    Myeloperoxidase
 Protein Family    Myeloperoxidase
 UniProt Gene Name    MPO [Similar Products]
 UniProt Synonym Gene Names    MPO [Similar Products]
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 NCBI Summary for MPO    Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
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 UniProt Comments for MPO    MPO: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain. Belongs to the peroxidase family. XPO subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.11.2.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: azurophil granule; extracellular space; lysosome; nucleus; secretory granule

Molecular Function: chromatin binding; heparin binding; peroxidase activity

Biological Process: defense response; defense response to bacterium; hydrogen peroxide catabolic process; negative regulation of apoptosis; response to oxidative stress

Disease: Alzheimer Disease; Myeloperoxidase Deficiency
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 Research Articles on MPO    1. Short-term atorvastatin therapy resulted in lipid lowering and anti-inflammatory activity in patients after AMI, independently of its effect on MPO gene expression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MPO antibodyPathways associated with anti-MPO antibody
 Reference Product  PubMed Publications
 PRTN3 antibody  >185 publications with MPO and PRTN3
 MYB antibody  >10 publications with MPO and MYB
 JAK2 antibody  >4 publications with MPO and JAK2
 ALB antibody  >4 publications with MPO and ALB
 ELANE antibody  >1 publications with MPO and ELANE
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 IL23-mediated Signaling Events Pathway antibodies  IL23-mediated Signaling Events Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Amb2 Integrin Signaling Pathway antibodies  Amb2 Integrin Signaling Pathway Diagram
Diseases associated with anti-MPO antibodyOrgans/Tissues associated with anti-MPO antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2156 publications with MPO and Inflammation
 Cardiovascular Diseases Antibodies  >1784 publications with MPO and Cardiovascular Diseases
 Necrosis Antibodies  >1208 publications with MPO and Necrosis
 Lung Diseases Antibodies  >1052 publications with MPO and Lung Diseases
 Reperfusion Injury Antibodies  >751 publications with MPO and Reperfusion Injury
 Kidney Diseases Antibodies  >570 publications with MPO and Kidney Diseases
 Edema Antibodies  >518 publications with MPO and Edema
 Drug Toxicity Antibodies  >509 publications with MPO and Drug Toxicity
 Hemorrhage Antibodies  >394 publications with MPO and Hemorrhage
 Heart Diseases Antibodies  >368 publications with MPO and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4422 publications with MPO and Blood
 Lung Antibodies  >1298 publications with MPO and Lung
 Kidney Antibodies  >622 publications with MPO and Kidney
 Brain Antibodies  >522 publications with MPO and Brain
 Bone Antibodies  >344 publications with MPO and Bone
 Bone Marrow Antibodies  >283 publications with MPO and Bone Marrow
 Eye Antibodies  >83 publications with MPO and Eye
 Lymph Node Antibodies  >75 publications with MPO and Lymph Node
 Thyroid Antibodies  >68 publications with MPO and Thyroid
 Embryonic Tissue Antibodies  >37 publications with MPO and Embryonic Tissue
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