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anti-MB antibody :: Myoglobin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS311106 anti-MB antibody
Unit / Price
1 mg  /  $590 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myoglobin (MB), Monoclonal Antibody

 Also Known As   

MAb to Myoglobin Cardiac

 Product Synonym Names    Monoclonal Antibody to Human Cardiac Myoglobin
 Product Gene Name   

anti-MB antibody

[Similar Products]
 Matching Pairs    Capture Antibody: Myoglobin Clone #4E2 (MBS311106)
Detection Antibody: Myoglobin Clone #7C3 (MBS311227)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 22; NC_000022.10 (36002811..36019401, complement). Location: 22q13.1
 OMIM    160000
 3D Structure    ModBase 3D Structure for P02144
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    4E2
 Host    Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Source: Ascites
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 Specificity    Myoglobin
Human cardiac myoglobin
 Purity/Purification    >90% pure (SDS-PAGE). Protein A chromatography
 Form/Format    Purified, Liquid
 Concentration    6.8mg/ml (Sigma protein assay kit) (lot specific)
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 Immunogen    Human cardiac myoglobin
 Affinity Constant    Not determined
 Buffer    PBS, pH 7.4
 Preservative    0.1% Sodium azide
 Important Note    Centrifuge before opening to ensure complete recovery of vial contents.
 Warnings    This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
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 Preparation and Storage    Store at 2 to 8 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MB antibody    Monoclonal Antibodies to Cardiac Markers
 Applications Tested/Suitable for anti-MB antibody   

EIA/ELISA, Immunoassay Antibody Pairs

 Application Notes for anti-MB antibody    Detection of human cardiac myoglobin in immunoassay. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Rec
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NCBI/Uniprot data below describe general gene information for MB. It may not necessarily be applicable to this product.
 NCBI GI #    44955888
 NCBI GeneID    4151
 NCBI Accession #    NP_976312.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_203378.1 [Other Products]
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 UniProt Primary Accession #    P02144 [Other Products]
 UniProt Secondary Accession #    Q52H51; Q5THY7 [Other Products]
 UniProt Related Accession #    P02144; Q8WVH6 [Other Products]
 Molecular Weight    17,184 Da [Similar Products]
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 NCBI Official Full Name    myoglobin
 NCBI Official Synonym Full Names    myoglobin
 NCBI Official Symbol    MB [Similar Products]
 NCBI Official Synonym Symbols   
PVALB; MGC13548
[Similar Products]
 NCBI Protein Information    myoglobin; OTTHUMP00000197919; OTTHUMP00000197921; OTTHUMP00000197922; OTTHUMP00000197935
 UniProt Protein Name    Myoglobin
 Protein Family    Myoglobin
 UniProt Gene Name    MB [Similar Products]
 UniProt Entry Name    MYG_HUMAN
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 NCBI Summary for MB    This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
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 UniProt Comments for MB    MB: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 22q13.1

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: slow-twitch skeletal muscle fiber contraction; response to hydrogen peroxide; oxygen transport; heart development; response to hypoxia; response to hormone stimulus; brown fat cell differentiation; enucleate erythrocyte differentiation
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 Research Articles on MB    1. These results show that glutathione reduces hydrogen peroxide-induced protein decomposition due to reduction of the C110-thiyl radical in WTwild type human Mb by electron transfer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-MB antibodyOrgans/Tissues associated with anti-MB antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7284 publications with MB and Neoplasms
 Myocardial Ischemia Antibodies  >4160 publications with MB and Myocardial Ischemia
 Congenital Abnormalities Antibodies  >1594 publications with MB and Congenital Abnormalities
 Necrosis Antibodies  >1042 publications with MB and Necrosis
 Neoplasm Metastasis Antibodies  >906 publications with MB and Neoplasm Metastasis
 Bacterial Infections Antibodies  >863 publications with MB and Bacterial Infections
 Neoplasms, Experimental Antibodies  >815 publications with MB and Neoplasms, Experimental
 Lung Diseases Antibodies  >737 publications with MB and Lung Diseases
 Drug Toxicity Antibodies  >720 publications with MB and Drug Toxicity
 Adenocarcinoma Antibodies  >710 publications with MB and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >4012 publications with MB and Heart
 Muscle Antibodies  >2906 publications with MB and Muscle
 Vascular Antibodies  >1704 publications with MB and Vascular
 Lung Antibodies  >1158 publications with MB and Lung
 Liver Antibodies  >834 publications with MB and Liver
 Nerve Antibodies  >617 publications with MB and Nerve
 Prostate Antibodies  >435 publications with MB and Prostate
 Eye Antibodies  >395 publications with MB and Eye
 Mouth Antibodies  >261 publications with MB and Mouth
 Embryonic Tissue Antibodies  >247 publications with MB and Embryonic Tissue
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