NP_001186945.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,831 Da
NCBI Official Full Name
N-acetyltransferase 6 isoform 2
NCBI Official Synonym Full Names
N-acetyltransferase 6 (GCN5-related)
NCBI Official Synonym Symbols
NCBI Protein Information
N-acetyltransferase 6; protein fusion-2
UniProt Protein Name
N-acetyltransferase 6
UniProt Synonym Protein Names
Protein fusion-2; Protein fus-2
UniProt Synonym Gene Names
UniProt Entry Name
NAT6_HUMAN
NCBI Summary for NAT6
This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
UniProt Comments for NAT6
NAT6: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. Belongs to the acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tyrosine; EC 2.3.1.-; Amino Acid Metabolism - phenylalanine; Lipid Metabolism - glycerophospholipid; Tumor suppressor; Secondary Metabolites Metabolism - limonene and pinene degradation; Acetyltransferase
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: cytoplasm
Molecular Function: N-acetyltransferase activity
Biological Process: metabolic process
Research Articles on NAT6
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Organs/Tissues associated with anti-NAT6 antibody
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