NP_058943.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sodium channel protein type 10 subunit alpha
NCBI Official Synonym Full Names
sodium channel, voltage-gated, type X, alpha subunit
NCBI Protein Information
sodium channel protein type 10 subunit alpha; sensory neuron sodium channel; peripheral nerve sodium channel 3; sodium channel type X alpha polypeptide; sodium channel protein type X subunit alpha; voltage-gated sodium channel subunit alpha Nav1.8; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage-gated, type 10, alpha polypeptide
UniProt Protein Name
Sodium channel protein type 10 subunit alpha
UniProt Synonym Protein Names
Peripheral nerve sodium channel 3; PN3; Sensory neuron sodium channel; Sodium channel protein type X subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.8
UniProt Synonym Gene Names
UniProt Entry Name
SCNAA_RAT
NCBI Summary for Scn10a
voltage-gated sodium channel that is resistant to tetrodotoxin [RGD, Feb 2006]
UniProt Comments for Scn10a
SCN10A: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms. Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.8/SCN10A subfamily.
Protein type: Membrane protein, multi-pass; Channel, sodium; Membrane protein, integral
Product References and Citations for anti-Scn10a antibody
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Dray A. (2008) Br. J. Anaesth. 101(1): 48-58. 4. Dray A., Read S.J (2007) Arthritis Res. Ther. 9(3): 212. 5. Samuels M.E., teMorshe R.H., Lynch M.E., Drenth J.P. (2008) Mol Pain. 4: 21.
Research Articles on Scn10a
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Diseases associated with anti-Scn10a antibody
Organs/Tissues associated with anti-Scn10a antibody
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