NP_032770.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
netrin-1
NCBI Official Synonym Full Names
netrin 1
NCBI Protein Information
netrin-1
UniProt Protein Name
Netrin-1
UniProt Entry Name
NET1_MOUSE
UniProt Comments for Ntn1
Function: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis
By similarity. Ref.1 Ref.2
Subunit structure: Binds to its receptors; DCC, UNC5A, UNC5B, UNC5C and probably UNC5D
By similarity. Binds to its receptor; DSCAM. Ref.7
Subcellular location: Secreted › extracellular space › extracellular matrix Ref.6.
Tissue specificity: In the embryo, widely expressed in the developing nervous system and in mesodermal tissues. Ref.2
Sequence similarities: Contains 3 laminin EGF-like domains.Contains 1 laminin N-terminal domain.Contains 1 NTR domain.
Research Articles on Ntn1
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Products associated with anti-Ntn1 antibody
Pathways associated with anti-Ntn1 antibody
Diseases associated with anti-Ntn1 antibody
Organs/Tissues associated with anti-Ntn1 antibody
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