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anti-BGLAP antibody :: Mouse OSTEOCALCIN Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211442 anti-BGLAP antibody
Unit / Price
0.2 mg  /  $320 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OSTEOCALCIN (BGLAP), Monoclonal Antibody

 Also Known As   


 Product Gene Name   

anti-BGLAP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P02820
 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    3H8H12D2A12F12
 Host    Mouse
 Species Reactivity    Human, Pig, Rabbit, Rat
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
 Buffer Solution    Phosphate buffered saline
 Target Species    Bovine
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-BGLAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BGLAP antibody

   Mouse anti Bovine Osteocalcin antibody, clone 3H8H12D2A12F12 recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19 or intact bovine osteocalcin. Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget's disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
 Applications Tested/Suitable for anti-BGLAP antibody   


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NCBI/Uniprot data below describe general gene information for BGLAP. It may not necessarily be applicable to this product.
 NCBI GI #    27806301
 NCBI GeneID    281646
 NCBI Accession #    NP_776674.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_174249.2 [Other Products]
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 UniProt Primary Accession #    P02820 [Other Products]
 UniProt Secondary Accession #    A7YEW1 [Other Products]
 UniProt Related Accession #    P02820 [Other Products]
 Molecular Weight    11,042 Da [Similar Products]
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 NCBI Official Full Name    osteocalcin preproprotein
 NCBI Official Synonym Full Names    bone gamma-carboxyglutamate (gla) protein
 NCBI Official Symbol    BGLAP [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein
 UniProt Protein Name    Osteocalcin
 UniProt Synonym Protein Names   
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
 Protein Family    Osteocalcin
 UniProt Gene Name    BGLAP [Similar Products]
 UniProt Synonym Gene Names    BGP [Similar Products]
 UniProt Entry Name    OSTCN_BOVIN
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 UniProt Comments for BGLAP    osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family.

Protein type: Secreted; Cell development/differentiation; Secreted, signal peptide

Cellular Component: extracellular region

Molecular Function: calcium ion binding

Biological Process: biomineral formation; regulation of bone mineralization
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 Research Articles on BGLAP    1. Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BGLAP antibodyDiseases associated with anti-BGLAP antibody
 Reference Product  PubMed Publications
 SPP1 antibody  >23 publications with BGLAP and SPP1
 BMP2 antibody  >13 publications with BGLAP and BMP2
 PTH antibody  >2 publications with BGLAP and PTH
 LEP antibody  >1 publications with BGLAP and LEP
 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >10 publications with BGLAP and Bone Diseases
 Osteoporosis Antibodies  >9 publications with BGLAP and Osteoporosis
 Inflammation Antibodies  >5 publications with BGLAP and Inflammation
 Nervous System Diseases Antibodies  >4 publications with BGLAP and Nervous System Diseases
 Calcinosis Antibodies  >3 publications with BGLAP and Calcinosis
 Kidney Diseases Antibodies  >2 publications with BGLAP and Kidney Diseases
 Cardiovascular Diseases Antibodies  >2 publications with BGLAP and Cardiovascular Diseases
 Pain Antibodies  >2 publications with BGLAP and Pain
 Renal Insufficiency Antibodies  >1 publications with BGLAP and Renal Insufficiency
 Hypertension Antibodies  >1 publications with BGLAP and Hypertension
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