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anti-OLIG1 antibody :: Mouse anti-Human, Mouse Olig1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS631740 anti-OLIG1 antibody
Unit / Price
0.1 mg  /  $605 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Olig1, Monoclonal Antibody

 Also Known As   

Olig1 (Oligodendrocyte Transcription Factor 1, Oligo1, Class B Basic Helix-loop-helix Protein 6, bHLHb6, Class E Basic Helix-loop-helix Protein 21, bHLHe21, BHLHB6, BHLHE21)

 Product Synonym Names    Anti -Olig1 (Oligodendrocyte Transcription Factor 1, Oligo1, Class B Basic Helix-loop-helix Protein 6, bHLHb6, Class E Basic Helix-loop-helix Protein 21, bHLHe21, BHLHB6, BHLHE21)
 Product Gene Name   

anti-OLIG1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 21; NC_000021.8 (34442450..34444728). Location: 21q22.11
 OMIM    606385
 3D Structure    ModBase 3D Structure for Q8TAK6
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    11C42
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Specificity    Recognizes endogenous human Olig1. Species Crossreactivity: mouse. Does not react with recombinant human Olig2 or recombinant human Olig3
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
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 Immunogen    Recombinant cooresponding to human Oligodendrocyte transcription factor-1, expressed in E. coli (XM_170977).
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-OLIG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-OLIG1 antibody

   Olig1 and Olig2, which have been implicated in oligodendrogenesis, are expressed in the region of the ventral ventricular zone of late embryonic spinal cord where oligodendrocyte progenitors appear. Olig3 is transiently expressed in different types of progenitors of embryonic central nervous system and then disappears in the course of development. In adult, expression of Olig3 is primarily detected in neural tissues.
 Product Categories/Family for anti-OLIG1 antibody    Antibodies; Abs to Transcription Factors
 Applications Tested/Suitable for anti-OLIG1 antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-OLIG1 antibody    Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: Western Blot: 0.5ug/ml
Immunohistochemistry: 8-25ug/ml detects Olig1 in paraffin- embedded human astrocytoma and glioma tissue sections.
ELISA: 0.5-1ug/ml. The detection limit for recombinant human Olig1 is ~0.5ng/ml.
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NCBI/Uniprot data below describe general gene information for OLIG1. It may not necessarily be applicable to this product.
 NCBI GI #    237757328
 NCBI GeneID    116448
 NCBI Accession #    NP_620450.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_138983.2 [Other Products]
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 UniProt Primary Accession #    Q8TAK6 [Other Products]
 UniProt Secondary Accession #    Q7RTS0 [Other Products]
 UniProt Related Accession #    Q8TAK6 [Other Products]
 Molecular Weight    27,905 Da [Similar Products]
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 NCBI Official Full Name    oligodendrocyte transcription factor 1
 NCBI Official Synonym Full Names    oligodendrocyte transcription factor 1
 NCBI Official Symbol    OLIG1 [Similar Products]
 NCBI Official Synonym Symbols   
BHLHB6; BHLHE21
[Similar Products]
 NCBI Protein Information    oligodendrocyte transcription factor 1; oligo1; class B basic helix-loop-helix protein 6; class E basic helix-loop-helix protein 21; oligodendrocyte lineage transcription factor 1; basic domain, helix-loop-helix protein, class B, 6; oligodendrocyte-specific bHLH transcription factor 1
 UniProt Protein Name    Oligodendrocyte transcription factor 1
 UniProt Synonym Protein Names   
Class B basic helix-loop-helix protein 6; bHLHb6; Class E basic helix-loop-helix protein 21
 Protein Family    Oligodendrocyte transcription factor
 UniProt Gene Name    OLIG1 [Similar Products]
 UniProt Synonym Gene Names    BHLHB6; BHLHE21; Oligo1; bHLHb6; bHLHe21 [Similar Products]
 UniProt Entry Name    OLIG1_HUMAN
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 UniProt Comments for OLIG1    OLIG1: Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Protein type: Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: nucleus

Molecular Function: protein dimerization activity; protein binding; DNA binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; neuron fate commitment
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 Research Articles on OLIG1    1. Olig1 is a Smad cofactor involved in TGF-beta-induced cell motility
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-OLIG1 antibodyPathways associated with anti-OLIG1 antibody
 Reference Product  PubMed Publications
 MBP antibody  >22 publications with OLIG1 and MBP
 SOX10 antibody  >21 publications with OLIG1 and SOX10
 NKX2-2 antibody  >18 publications with OLIG1 and NKX2-2
 SHH antibody  >12 publications with OLIG1 and SHH
 GFAP antibody  >10 publications with OLIG1 and GFAP
 ID4 antibody  >6 publications with OLIG1 and ID4
 NKX6-2 antibody  >4 publications with OLIG1 and NKX6-2
 SMAD2 antibody  >2 publications with OLIG1 and SMAD2
 Products by Pathway  Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
Diseases associated with anti-OLIG1 antibodyOrgans/Tissues associated with anti-OLIG1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >23 publications with OLIG1 and Neoplasms
 Necrosis Antibodies  >4 publications with OLIG1 and Necrosis
 Nerve Degeneration Antibodies  >3 publications with OLIG1 and Nerve Degeneration
 Inflammation Antibodies  >3 publications with OLIG1 and Inflammation
 Abnormalities, Multiple Antibodies  >3 publications with OLIG1 and Abnormalities, Multiple
 Hyperplasia Antibodies  >2 publications with OLIG1 and Hyperplasia
 Diabetes Mellitus, Experimental Antibodies  >1 publications with OLIG1 and Diabetes Mellitus, Experimental
 Edema Antibodies  >1 publications with OLIG1 and Edema
 Carcinoma Antibodies  >1 publications with OLIG1 and Carcinoma
 Abnormalities, Drug-Induced Antibodies  >1 publications with OLIG1 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >97 publications with OLIG1 and Brain
 Kidney Antibodies  >1 publications with OLIG1 and Kidney
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