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anti-OSCAR antibody :: Mouse anti-Human Osteoclast Associated Receptor (OSCAR) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090644
Western Blot (WB)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $145 +1 FREE 8GB USB
0.1 mg  /  $185 +1 FREE 8GB USB
0.2 mg  /  $235 +1 FREE 8GB USB
1 mg  /  $540 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Osteoclast Associated Receptor (OSCAR), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to Osteoclast Associated Receptor (OSCAR)

 Product Synonym Names    PIGR3; Osteoclast Associated,Immunoglobulin-Like Receptor; Polymeric immunoglobulin receptor 3; Poly-Ig receptor 3
 Product Gene Name   

anti-OSCAR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF251702 mRNA
 3D Structure    ModBase 3D Structure for Q8IYS5
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 Clonality    Monoclonal
 Isotype    IgG
 Clone Number    D4
 Host    Mouse
 Species Reactivity    Human
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 Specificity    The antibody is a mouse monoclonal antibody raised against OSCAR. It has been selected for its ability to recognize OSCAR in immunohistochemical staining and western blotting.
 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Liquid
 Concentration    1mg/mL (lot specific)
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 Immunogen    Recombinant Osteoclast Associated Receptor (OSCAR)
 Buffer Formulation    0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-OSCAR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-OSCAR antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-OSCAR antibody    Western Blot: 0.5-5ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
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 Western Blot (WB) of anti-OSCAR antibody    (Figure. Western Blot; Sample: Recombinant OSCAR, Human.)
anti-OSCAR antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for OSCAR. It may not necessarily be applicable to this product.
 NCBI GI #    537544647
 NCBI GeneID    126014
 NCBI Accession #    NP_001269278.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001282349.1 [Other Products]
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 UniProt Primary Accession #    Q8IYS5 [Other Products]
 UniProt Secondary Accession #    Q5GRG5; Q8N763; Q8NHL4; Q8WXQ0; Q8WXQ1; Q8WXQ2; B7WNS2 [Other Products]
 UniProt Related Accession #    Q8IYS5 [Other Products]
 Molecular Weight    27,629 Da
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 NCBI Official Full Name    osteoclast-associated immunoglobulin-like receptor isoform 6
 NCBI Official Synonym Full Names    osteoclast associated, immunoglobulin-like receptor
 NCBI Official Symbol    OSCAR [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    osteoclast-associated immunoglobulin-like receptor
 UniProt Protein Name    Osteoclast-associated immunoglobulin-like receptor
 UniProt Synonym Protein Names   
Polymeric immunoglobulin receptor 3; PIgR-3; PIgR3; Poly-Ig receptor 3
 Protein Family    Osteoclast-associated immunoglobulin-like receptor
 UniProt Gene Name    OSCAR [Similar Products]
 UniProt Synonym Gene Names    Osteoclast-associated receptor; hOSCAR; PIgR-3; PIgR3; Poly-Ig receptor 3 [Similar Products]
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 NCBI Summary for OSCAR    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
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 UniProt Comments for OSCAR    OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: extracellular region; integral component of membrane; plasma membrane

Biological Process: neutrophil degranulation; regulation of immune response
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 Research Articles on OSCAR    1. OSCAR can play a proinflammatory role in monocyte-derived cells and may contribute crucially on multiple levels to rheumatoid arthritis pathogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-OSCAR antibodyPathways associated with anti-OSCAR antibody
 Reference Product  PubMed Publications
 NFATC1 antibody  >46 publications with OSCAR and NFATC1
 SYK antibody  >5 publications with OSCAR and SYK
 TYROBP antibody  >5 publications with OSCAR and TYROBP
 Products by Pathway  Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
Diseases associated with anti-OSCAR antibodyOrgans/Tissues associated with anti-OSCAR antibody
 Disease Name  Pubmed Publications
 Death Antibodies  >128 publications with OSCAR and Death
 Lung Diseases Antibodies  >94 publications with OSCAR and Lung Diseases
 Lung Neoplasms Antibodies  >62 publications with OSCAR and Lung Neoplasms
 Heart Diseases Antibodies  >48 publications with OSCAR and Heart Diseases
 Bone Resorption Antibodies  >46 publications with OSCAR and Bone Resorption
 Necrosis Antibodies  >43 publications with OSCAR and Necrosis
 Inflammation Antibodies  >42 publications with OSCAR and Inflammation
 Kidney Diseases Antibodies  >35 publications with OSCAR and Kidney Diseases
 Liver Neoplasms Antibodies  >33 publications with OSCAR and Liver Neoplasms
 Neoplasms, Experimental Antibodies  >32 publications with OSCAR and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >264 publications with OSCAR and Blood
 Brain Antibodies  >146 publications with OSCAR and Brain
 Lung Antibodies  >105 publications with OSCAR and Lung
 Heart Antibodies  >90 publications with OSCAR and Heart
 Liver Antibodies  >73 publications with OSCAR and Liver
 Skin Antibodies  >64 publications with OSCAR and Skin
 Bone Marrow Antibodies  >51 publications with OSCAR and Bone Marrow
 Eye Antibodies  >45 publications with OSCAR and Eye
 Connective Tissue Antibodies  >26 publications with OSCAR and Connective Tissue
 Uterus Antibodies  >18 publications with OSCAR and Uterus
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