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anti-PAP antibody :: Mouse anti-PAP 100% PAP Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS530305 anti-PAP antibody
Unit / Price
1 mg  /  $230 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PAP, Monoclonal Antibody

★Popular Item★
 Also Known As   

PAP antibody

 Product Synonym Names    Monoclonal PAP; Anti-PAP; Prostatic Acid Phosphatase; Anti PAP; PAP
 Product Gene Name   

anti-PAP antibody

[Similar Products]
 Matching Pairs    Capture Antibody: PAP Clone #M01010921 (MBS530305)
Detection Antibody: PAP Clone #M01010922 (MBS530241)
Comments: Good pair for ELISA and IRMA
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    171790
 3D Structure    ModBase 3D Structure for P15309
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    M01010921
 Host    Mouse
 Species Reactivity    PAP 100%
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 Specificity    Human PAP
 Form/Format    Purified mouse ascites by Protein A affinity chromatography, supplied in PBS buffer, pH 7.5, with 0.1% sodium azide.
 Concentration    2.2 mg/mL (lot specific)
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 Immunogen    Higly pure human PAP.
 Additional Remarks    This clone is excellent for ELISA and IRMA.
 Affinity Constant    1 x 109 L/M
 Biological Significance    Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
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 Preparation and Storage    Store at 4C.
 Other Notes    Small volumes of anti-PAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PAP antibody

   Mouse monoclonal PAP antibody
 Product Categories/Family for anti-PAP antibody    Cancer
 Applications Tested/Suitable for anti-PAP antibody   

ELISA (EIA)

 Application Notes for anti-PAP antibody    Matched pair antibody available for PAP antibody: MBS530241
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NCBI/Uniprot data below describe general gene information for PAP. It may not necessarily be applicable to this product.
 NCBI GI #    6382064
 NCBI GeneID    55
 NCBI Accession #    NP_001090.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001099.4 [Other Products]
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 UniProt Primary Accession #    P15309 [Other Products]
 UniProt Secondary Accession #    Q5FBY0; Q96KY0; Q96QK9; Q96QM0; D3DNC6 [Other Products]
 UniProt Related Accession #    P15309 [Other Products]
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 NCBI Official Full Name    prostatic acid phosphatase isoform PAP
 NCBI Official Synonym Full Names    acid phosphatase, prostate
 NCBI Official Symbol    ACPP [Similar Products]
 NCBI Official Synonym Symbols   
ACP3; 5'-NT; ACP-3
[Similar Products]
 NCBI Protein Information    prostatic acid phosphatase
 UniProt Protein Name    Prostatic acid phosphatase
 UniProt Synonym Protein Names   
5'-nucleotidase (EC:3.1.3.5); 5'-NT
 Protein Family    Papain
 UniProt Gene Name    ACPP [Similar Products]
 UniProt Synonym Gene Names    PAP; 5'-NT; TMPase [Similar Products]
 UniProt Entry Name    PPAP_HUMAN
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 NCBI Summary for PAP    This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
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 UniProt Comments for PAP    ACPP: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.2; Phosphatase; EC 3.1.3.5; Cofactor and Vitamin Metabolism - riboflavin

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: multivesicular body; extracellular space; Golgi cisterna; lysosomal membrane; apical part of cell; integral to membrane; plasma membrane; vesicle membrane; intracellular; nucleus; filopodium; secretory granule

Molecular Function: 5'-nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity

Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process
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 Research Articles on PAP    1. ACPP increases significantly in epithelial cells of ovarian carcinoma, which indicates that it may be a candidate biomarker for diagnosis of epithelia-derived ovarian cancer in women.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PAP antibodyPathways associated with anti-PAP antibody
 Reference Product  PubMed Publications
 SLC45A3 antibody  >1 publications with PAP and SLC45A3
 KLK3 antibody  >1 publications with PAP and KLK3
 Products by Pathway  Pathway Diagram
 Riboflavin Metabolism Pathway antibodies  Riboflavin Metabolism Pathway Diagram
 Riboflavin Metabolism Pathway antibodies  Riboflavin Metabolism Pathway Diagram
Diseases associated with anti-PAP antibodyOrgans/Tissues associated with anti-PAP antibody
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >9 publications with PAP and Prostatic Neoplasms
 Inflammation Antibodies  >4 publications with PAP and Inflammation
 Fibrosis Antibodies  >3 publications with PAP and Fibrosis
 Breast Neoplasms Antibodies  >3 publications with PAP and Breast Neoplasms
 Necrosis Antibodies  >3 publications with PAP and Necrosis
 Hyperplasia Antibodies  >3 publications with PAP and Hyperplasia
 Ovarian Neoplasms Antibodies  >2 publications with PAP and Ovarian Neoplasms
 Urinary Bladder Neoplasms Antibodies  >2 publications with PAP and Urinary Bladder Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with PAP and Neoplasm Metastasis
 Myocardial Infarction Antibodies  >2 publications with PAP and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with PAP and Blood
 Prostate Antibodies  >13 publications with PAP and Prostate
 Brain Antibodies  >6 publications with PAP and Brain
 Muscle Antibodies  >4 publications with PAP and Muscle
 Bone Antibodies  >4 publications with PAP and Bone
 Ovary Antibodies  >2 publications with PAP and Ovary
 Skin Antibodies  >2 publications with PAP and Skin
 Nerve Antibodies  >1 publications with PAP and Nerve
 Connective Tissue Antibodies  >1 publications with PAP and Connective Tissue
 Bone Marrow Antibodies  >1 publications with PAP and Bone Marrow
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