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anti-PTHLH antibody :: Mouse anti-Human PARATHYROID HORMONE RELATED PEPTIDE Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211856 anti-PTHLH antibody
Unit / Price
0.2 mg  /  $440 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PARATHYROID HORMONE RELATED PEPTIDE (PTHLH), Monoclonal Antibody

 Also Known As   

MOUSE ANTI HUMAN PARATHYROID HORMONE RELATED PEPTIDE

 Product Gene Name   

anti-PTHLH antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    K-P-G-K-R- K-E-Q-E-K- K-K-R-R-T
 Chromosome Location    Chromosome: 12; NC_000012.11 (28111017..28124916, complement). Location: 12p12.1-p11.2
 OMIM    168470
 3D Structure    ModBase 3D Structure for P12272
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 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    BGN/09/5215
 Host    Mouse
 Species Reactivity    Human
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 Specificity    PARATHYROID HORMONE RELATED PEPTIDE
This item is specific for Parathyroid hormone related peptide (PTHrP). PTHrP is involved in the formation of mammary glands and teeth, and it regulates bone development. It shares the same N-terminal as Parathyroid hormone (PTH) which allows it to bind to Parathyroid Hormone Receptor 1 (PTHR1). This receptor is responsible for hypercalcemia, which is an increase of calcium in the blood.
 Form/Format    Purified (Purified IgG - liquid)
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
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 Immunogen    Synthetic peptide corresponding to the amino acids 93-107 of human PTHrP conjugated to Keyhole limpet Haemocyanin (KLH).
 Reactivity Note    Bovine: Expected from Sequence
Chimpanzee: Expected from Sequence
Dog: Expected from Sequence
Horse: Expected from Sequence
Pig: Expected from Sequence
Rabbit: Expected from Sequence
Rat: Expected from Sequence
Rhesus Monkey: Expected from Sequence
 Preparation    Purified IgG prepared by affinity chromatography on Protein A
 Preservative Stabilizers    0.09% Sodium Azide (NaN3)
 Buffer Solution    Phosphate buffered saline
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 Preparation and Storage    Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of dispatch.
 Other Notes    Small volumes of anti-PTHLH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PTHLH antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for PTHLH. It may not necessarily be applicable to this product.
 NCBI GI #    4506269
 NCBI GeneID    5744
 NCBI Accession #    NP_002811.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002820.2 [Other Products]
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 UniProt Primary Accession #    P12272 [Other Products]
 UniProt Secondary Accession #    Q15251; Q6FH74 [Other Products]
 UniProt Related Accession #    P12272 [Other Products]
 Molecular Weight    20,194 Da [Similar Products]
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 NCBI Official Full Name    parathyroid hormone-related protein isoform 2 preproprotein
 NCBI Official Synonym Full Names    parathyroid hormone-like hormone
 NCBI Official Symbol    PTHLH [Similar Products]
 NCBI Official Synonym Symbols   
HHM; PLP; BDE2; PTHR; PTHRP
[Similar Products]
 NCBI Protein Information    parathyroid hormone-related protein; PTH-rP; osteostatin; PTH-related protein; parathyroid hormone-like related protein; parathyroid hormone-related protein preproprotein
 UniProt Protein Name    Parathyroid hormone-related protein
 UniProt Synonym Protein Names   
Parathyroid hormone-like protein; PLPCleaved into the following 3 chains:PTHrP[1-36]PTHrP[38-94]Osteostatin; Alternative name(s):; PTHrP[107-139]
 Protein Family    Parathyroid hormone-related protein
 UniProt Gene Name    PTHLH [Similar Products]
 UniProt Synonym Gene Names    PTHRP; PTH-rP; PTHrP; PLP [Similar Products]
 UniProt Entry Name    PTHR_HUMAN
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PTHLH antibodyPathways associated with anti-PTHLH antibody
 Reference Product  PubMed Publications
 PTH1R antibody  >9 publications with PTHLH and PTH1R
 IL6 antibody  >2 publications with PTHLH and IL6
 KPNB1 antibody  >1 publications with PTHLH and KPNB1
 CDK2 antibody  >1 publications with PTHLH and CDK2
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Signaling Events Mediated By The Hedgehog Family Pathway antibodies  Signaling Events Mediated By The Hedgehog Family Pathway Diagram
Diseases associated with anti-PTHLH antibodyOrgans/Tissues associated with anti-PTHLH antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >725 publications with PTHLH and Neoplasms
 Hypercalcemia Antibodies  >607 publications with PTHLH and Hypercalcemia
 Bone Neoplasms Antibodies  >230 publications with PTHLH and Bone Neoplasms
 Bone Resorption Antibodies  >139 publications with PTHLH and Bone Resorption
 Breast Neoplasms Antibodies  >116 publications with PTHLH and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >111 publications with PTHLH and Carcinoma, Squamous Cell
 Urogenital Neoplasms Antibodies  >110 publications with PTHLH and Urogenital Neoplasms
 Lung Neoplasms Antibodies  >101 publications with PTHLH and Lung Neoplasms
 Kidney Neoplasms Antibodies  >73 publications with PTHLH and Kidney Neoplasms
 Leukemia Antibodies  >71 publications with PTHLH and Leukemia
 Organ/Tissue Name  Pubmed Publications
 Parathyroid Antibodies  >1177 publications with PTHLH and Parathyroid
 Kidney Antibodies  >142 publications with PTHLH and Kidney
 Lung Antibodies  >126 publications with PTHLH and Lung
 Skin Antibodies  >70 publications with PTHLH and Skin
 Embryonic Tissue Antibodies  >57 publications with PTHLH and Embryonic Tissue
 Prostate Antibodies  >42 publications with PTHLH and Prostate
 Uterus Antibodies  >32 publications with PTHLH and Uterus
 Mammary Gland Antibodies  >29 publications with PTHLH and Mammary Gland
 Brain Antibodies  >26 publications with PTHLH and Brain
 Pancreas Antibodies  >24 publications with PTHLH and Pancreas
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