NP_001024743.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Protein PDK-1, isoform b
NCBI Protein Information
Protein PDK-1
UniProt Protein Name
3-phosphoinositide-dependent protein kinase 1
UniProt Synonym Protein Names
Pdk-class protein kinase 1
UniProt Entry Name
PDPK1_CAEEL
UniProt Comments for pdk-1
Function: Involved in the daf-2/insulin receptor-like transduction pathway, which controls longevity and prevents developmental arrest at the dauer stage. Phosphorylates and activates sgk-1, akt-1 and akt-2. Ref.1 Ref.3
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Subunit structure: Interacts directly with sgk-1, akt-1 and akt-2. Ref.3
Subcellular location: Cytoplasm
By similarity.
Developmental stage: Expressed in late stage embryos and throughout life. At L1, expressed in neurons, intestinal cells and hypodermal cells. In adults, expressed in the somatic gonad. Ref.1
Sequence similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.Contains 1 protein kinase domain.
Research Articles on pdk-1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-pdk-1 antibody
Organs/Tissues associated with anti-pdk-1 antibody
|