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anti-PLAA antibody :: Mouse anti-Human, Mouse PLAA Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2542029 anti-PLAA antibody
Unit / Price
0.06 mL  /  $215 +1 FREE 8GB USB
0.12 mL  /  $330 +1 FREE 8GB USB
0.2 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PLAA, Monoclonal Antibody

 Also Known As   

PLAA Antibody

 Product Synonym Names    DOA1; FLJ11281; FLJ12699; PLA2P; PLAA; PLAP
 Product Gene Name   

anti-PLAA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AK001642 mRNA
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 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Purity/Purification    Protein A purification
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 Immunogen    PLAA fusion protein ag3224
 Buffer    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-PLAA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-PLAA antibody

   Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain and PUL domain. Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD. Recent finding revealed that PLAA served as a novel nociveptive mediator after incision, and its expression level is regulated by miR-203.
 Applications Tested/Suitable for anti-PLAA antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-PLAA antibody    WB: 1:500-1:5000
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NCBI/Uniprot data below describe general gene information for PLAA. It may not necessarily be applicable to this product.
 NCBI GI #    1010225920
 NCBI GeneID    9373
 NCBI GenBank Nucleotide #    NM_001321546.1 [Other Products]
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 UniProt Secondary Accession #    Q53EU5; Q5VY33; Q9NUL8; Q9NVE9; Q9UF53; Q9Y5L1 [Other Products]
 UniProt Related Accession #    Q9Y263 [Other Products]
 Molecular Weight    Calculated MW: 738aa; 81 kDa
Observed MW: 72-74 kDa
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 NCBI Official Full Name    phospholipase A-2-activating protein isoform 2
 NCBI Official Synonym Full Names    phospholipase A2 activating protein
 NCBI Official Symbol    PLAA [Similar Products]
 NCBI Official Synonym Symbols   
DOA1; PLAP; PLA2P
[Similar Products]
 NCBI Protein Information    phospholipase A-2-activating protein
 UniProt Protein Name    Phospholipase A-2-activating protein
 Protein Family    Phospholipase A-2-activating protein
 UniProt Gene Name    PLAA [Similar Products]
 UniProt Synonym Gene Names    PLAP; PLA2P; PLAP [Similar Products]
 UniProt Entry Name    PLAP_HUMAN
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 UniProt Comments for PLAA    PLAA: phospholipase A2 activating protein. A regulator of the production of eicosanoids and prostaglandin E(2) in immune and inflammatory responses. Belongs to the WD repeat PLAP family.

Protein type: Activator

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; ubiquitin binding

Biological Process: phospholipid metabolic process; proteasomal ubiquitin-dependent protein catabolic process; signal transduction
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 Research Articles on PLAA    1. This review provides evidence that 1,25-dihydroxy vitamin D3 stimulates PLA2 via PLAA and CaMKII, a process initiated by Pdia3/PLAA interaction, which further triggers CaMKII-dependent PLA2 activation. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to PLAA Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS2044461  APC-Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAA)  MBS2542029  PLAA Antibody
 MBS2044464  Cy3-Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAA)  MBS2009910  Recombinant Phospholipase A2 Activating Protein (PLAA)
 MBS2044465  Cy3-Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAA)  MBS2044455  PE-Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAA)
 MBS2009254  Recombinant Phospholipase A2 Activating Protein (PLAA)  MBS9216363  Rabbit Anti-PLAA Polyclonal Antibody
 MBS960842  Recombinant Mouse Phospholipase A-2-activating protein (Plaa)  MBS2044462  Cy3-Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAA)
Products associated with anti-PLAA antibodyPathways associated with anti-PLAA antibody
 Reference Product  PubMed Publications
 VCP antibody  >4 publications with PLAA and VCP
 YOD1 antibody  >1 publications with PLAA and YOD1
 UFD1L antibody  >1 publications with PLAA and UFD1L
 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
Diseases associated with anti-PLAA antibodyOrgans/Tissues associated with anti-PLAA antibody
 Disease Name  Pubmed Publications
 Poisoning Antibodies  >61 publications with PLAA and Poisoning
 Liver Diseases Antibodies  >49 publications with PLAA and Liver Diseases
 Drug-Induced Liver Injury Antibodies  >48 publications with PLAA and Drug-Induced Liver Injury
 Drug-Related Side Effects and Adverse Reactions Antibodies  >36 publications with PLAA and Drug-Related Side Effects and Adverse Reactions
 Nervous System Diseases Antibodies  >18 publications with PLAA and Nervous System Diseases
 Necrosis Antibodies  >13 publications with PLAA and Necrosis
 Neurotoxicity Syndromes Antibodies  >10 publications with PLAA and Neurotoxicity Syndromes
 Disease Models, Animal Antibodies  >8 publications with PLAA and Disease Models, Animal
 Kidney Diseases Antibodies  >8 publications with PLAA and Kidney Diseases
 Lung Diseases Antibodies  >6 publications with PLAA and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >145 publications with PLAA and Liver
 Blood Antibodies  >93 publications with PLAA and Blood
 Kidney Antibodies  >20 publications with PLAA and Kidney
 Brain Antibodies  >14 publications with PLAA and Brain
 Lung Antibodies  >13 publications with PLAA and Lung
 Vascular Antibodies  >9 publications with PLAA and Vascular
 Bone Antibodies  >6 publications with PLAA and Bone
 Muscle Antibodies  >5 publications with PLAA and Muscle
 Connective Tissue Antibodies  >5 publications with PLAA and Connective Tissue
 Adipose Tissue Antibodies  >4 publications with PLAA and Adipose Tissue
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