Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow POU2F1 rightarrow Monoclonal POU2F1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Brain Derived Neurotrophic Factor (BDNF) ELISA Kit
 • LAS1L Antibody
 • A Disintegrin and Metalloprotease 19 (ADAM19) ELISA Kit
 • CA15-3 Antibody
 • GUK1 ELISA Kit
 • Kim-1 ELISA Kit
 • CSF1R-CD115-CD6 Recombinant Protein
 • 14-3-3 theta-tau Antibody
 • Collagen Type II (COL2) ELISA Kit
 • A1BG Antibody
 • C-type lectin domain family 16, member A (CLEC16A) ELISA Kit
 • Adiponectin (ADIPOQ) Antibody
 • CAT Antibody
 • ZW10 Interactor 1 (Zwint) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-POU2F1 antibody :: Mouse anti-Human POU2F1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120010
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

POU2F1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human POU2F1

 Product Synonym Names    POU domain, class 2, transcription factor 1; OCT1; OTF1
 Product Gene Name   

anti-POU2F1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    164175
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    POU5I097
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-POU2F1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-POU2F1 antibody

   Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). [UniProtKB Function]
 Applications Tested/Suitable for anti-POU2F1 antibody   

Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

Section Bar
 Quality Control of anti-POU2F1 antibody    Western blot analysis of immunized recombinant protein, using anti-POU2F1 monoclonal antibody.
anti-POU2F1 antibody Quality Control image
Section Bar
 Quality Control #2 of anti-POU2F1 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-POU2F1 antibody Quality Control #2 image
Section Bar
 Western Blot (WB) of anti-POU2F1 antibody    Detection of human POU2F1 by Western blot.

Samples: Whole cell lysate (50 ug) from HEK293 cells. [Lot No. POU5I097-1]

Predicted molecular weight: 76 kDa
anti-POU2F1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunocytochemistry (ICC) of anti-POU2F1 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-POU2F1 mAb. [Lot No. POU5I097-1]
anti-POU2F1 antibody Immunocytochemistry (ICC) (ICC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for POU2F1. It may not necessarily be applicable to this product.
 NCBI GI #    30354476
 NCBI GeneID    5451
 NCBI Accession #    BC052274 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q5TBT7; Q6PK46; Q8NEU9; Q9BPV1; B1AL91; B1AL93; B4E029; J3KP77 [Other Products]
 UniProt Related Accession #    P14859 [Other Products]
 Molecular Weight    72,082 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens POU class 2 homeobox 1, mRNA
 NCBI Official Synonym Full Names    POU class 2 homeobox 1
 NCBI Official Symbol    POU2F1 [Similar Products]
 NCBI Official Synonym Symbols   
OCT1; OTF1; oct-1B
[Similar Products]
 NCBI Protein Information    POU domain, class 2, transcription factor 1; NF-A1; OTF-1; Octamer-binding transcription factor-1; oct-1; octamer-binding protein 1; octamer-binding transcription factor 1
 UniProt Protein Name    POU domain, class 2, transcription factor 1
 UniProt Synonym Protein Names   
NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1
 Protein Family    POU domain, class 2, transcription factor
 UniProt Gene Name    POU2F1 [Similar Products]
 UniProt Entry Name    PO2F1_HUMAN
Section Bar
 NCBI Summary for POU2F1    The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]
Section Bar
 UniProt Comments for POU2F1    Oct1: a ubiquitous transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. Phosphorylation apparently inhibits its interaction with DNA. Four splice variant isoforms have been described. Isoform 2 is lymphocyte specific.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: nucleoplasm; transcription factor complex; intracellular membrane-bound organelle; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase III promoter; positive regulation of transcription from RNA polymerase II promoter; gene expression; negative regulation of transcription, DNA-dependent; olfactory placode formation
Table BarTOPTable Bar
 Research Articles on POU2F1    1. we demonstrate that the Oct-1 transcription factor, commonly considered pro-proliferative, indeed facilitates IFN-gamma induced apoptosis in 5637 bladder carcinoma cells
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-POU2F1 antibodyPathways associated with anti-POU2F1 antibody
 Reference Product  PubMed Publications
 HCFC1 antibody  >388 publications with POU2F1 and HCFC1
 SP1 antibody  >41 publications with POU2F1 and SP1
 POU2AF1 antibody  >27 publications with POU2F1 and POU2AF1
 SOX2 antibody  >6 publications with POU2F1 and SOX2
 TBP antibody  >4 publications with POU2F1 and TBP
 XRCC5 antibody  >3 publications with POU2F1 and XRCC5
 BRCA1 antibody  >3 publications with POU2F1 and BRCA1
 SNAPC4 antibody  >2 publications with POU2F1 and SNAPC4
 PRKDC antibody  >1 publications with POU2F1 and PRKDC
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Initiation Pathway antibodies  RNA Polymerase III Transcription Initiation Pathway Diagram
Diseases associated with anti-POU2F1 antibodyOrgans/Tissues associated with anti-POU2F1 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >14 publications with POU2F1 and Necrosis
 Inflammation Antibodies  >13 publications with POU2F1 and Inflammation
 Nervous System Diseases Antibodies  >9 publications with POU2F1 and Nervous System Diseases
 Kidney Diseases Antibodies  >6 publications with POU2F1 and Kidney Diseases
 Hepatitis Antibodies  >6 publications with POU2F1 and Hepatitis
 Carcinoma, Hepatocellular Antibodies  >4 publications with POU2F1 and Carcinoma, Hepatocellular
 Brain Diseases Antibodies  >4 publications with POU2F1 and Brain Diseases
 Liver Diseases Antibodies  >4 publications with POU2F1 and Liver Diseases
 Liver Neoplasms Antibodies  >3 publications with POU2F1 and Liver Neoplasms
 Cholestasis Antibodies  >3 publications with POU2F1 and Cholestasis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >132 publications with POU2F1 and Blood
 Liver Antibodies  >40 publications with POU2F1 and Liver
 Kidney Antibodies  >34 publications with POU2F1 and Kidney
 Brain Antibodies  >31 publications with POU2F1 and Brain
 Embryonic Tissue Antibodies  >17 publications with POU2F1 and Embryonic Tissue
 Vascular Antibodies  >14 publications with POU2F1 and Vascular
 Lung Antibodies  >13 publications with POU2F1 and Lung
 Spleen Antibodies  >12 publications with POU2F1 and Spleen
 Muscle Antibodies  >11 publications with POU2F1 and Muscle
 Thymus Antibodies  >8 publications with POU2F1 and Thymus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions