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anti-PP2A alpha antibody :: Mouse PP2A alpha Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS375097 anti-PP2A alpha antibody
Unit / Price
0.1 mL  /  $415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PP2A alpha, Monoclonal Antibody

★Popular Item★
 Also Known As   

Mouse Anti-PP2A alpha (methyl L309) [2A10]

 Product Synonym Names    PP2A alpha antibody; PP2A C antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Ac antibody; PP2CA antibody; PPP2CA antibody; Protein phosphatase 2, catalytic subunit, alpha isoform antibody; Replication protein C antibody
 Product Gene Name   

anti-PP2A alpha antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2A10
 Host    Mouse
 Species Reactivity    Mouse, Human, Saccharomyces cerevisiae
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 Specificity    Alpha + beta isoforms of PP2A C
 Purity/Purification    Protein G
 Form/Format    Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
 Concentration    1mg/ml (lot specific)
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 Target Antigen    PP2A alpha (methyl L309)
 Immunogen    C-terminal peptide (Methyl-Leu309) of human PP2A catalic subunit.
 Myeloma/fusion Partners    X63-Ag8.653
 Health & Safty    Products that contain sodium azide (a poisonous and hazardous substance) should be handled by trained staffs only.
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 Preparation and Storage    Store at 4 degree C for one month, or in small aliquots at -20 degree C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
 Other Notes    Small volumes of anti-PP2A alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PP2A alpha antibody   

Western Blot (WB), Immunoprecipitation (IP)

 Application Notes for anti-PP2A alpha antibody    Optimal antibody dilution should be determined by titration, however as a guideline start at 1:500 for Wester Blot.
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Product References and Citations for anti-PP2A alpha antibody

   Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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