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anti-PKP3 antibody :: Mouse Plakophilin 3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS5307038 anti-PKP3 antibody
Unit / Price
0.1 mg  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Plakophilin 3 (PKP3), Monoclonal Antibody

 Also Known As   

Mouse monoclonal Plakophilin 3 antibody

 Product Synonym Names    Plakophilin 3 antibody
 Product Gene Name   

anti-PKP3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    Z98265 mRNA
 3D Structure    ModBase 3D Structure for Q9Y446
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    12B11F8
 Host    Mouse
 Species Reactivity    Canine, Human, Mouse, Swine
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 Specificity    Reacts with an epitope located between residues 779-793 in human plakophilin-3
 Form/Format    Supplied in PBS containing 0.09% sodium azide
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 Immunogen    Plakophilin 3 antibody was raised in Mouse using a synthetic peptide corresponding to amino acid residues 779-793 of human plakophilin-3 coupled to keyhole limpet hemocyanin (KLHRDFRAKGYRKED) as the immunogen.
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 Other Notes    Small volumes of anti-PKP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PKP3 antibody    Cell Biology
 Applications Tested/Suitable for anti-PKP3 antibody   

Immunohistochemistry (IHC) Formalin, Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-PKP3 antibody    IHC: 1:25-1:100
WB: 1:100-1:1000
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NCBI/Uniprot data below describe general gene information for PKP3. It may not necessarily be applicable to this product.
 NCBI GI #    4995641
 NCBI GeneID    11187
 NCBI Accession #    CAB44310.1 [Other Products]
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 UniProt Primary Accession #    Q9Y446 [Other Products]
 UniProt Secondary Accession #    Q53EX8; F8J390 [Other Products]
 UniProt Related Accession #    Q9Y446 [Other Products]
 Molecular Weight    88,655 Da [Similar Products]
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 NCBI Official Full Name    plakophilin 3
 NCBI Official Synonym Full Names    plakophilin 3
 NCBI Official Symbol    PKP3 [Similar Products]
 NCBI Protein Information    plakophilin-3
 UniProt Protein Name    Plakophilin-3
 Protein Family    Plakophilin
 UniProt Gene Name    PKP3 [Similar Products]
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 NCBI Summary for PKP3    This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
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 UniProt Comments for PKP3    plakophilin 3: a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells and dendritic reticular cells of lymphatic follicles.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cell-cell adherens junction; intercellular junction; plasma membrane

Molecular Function: alpha-catenin binding; cell adhesion molecule binding
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 Research Articles on PKP3    1. Children with low 25-hydroxyvitamin D and TMEM16J rs7111432-AA or PKP3 rs10902158-GG polymorphisms were at increased risk for tuberculosis or death.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PKP3 antibodyPathways associated with anti-PKP3 antibody
 Reference Product  PubMed Publications
 DSP antibody  >3 publications with PKP3 and DSP
 DSG3 antibody  >2 publications with PKP3 and DSG3
 DSG2 antibody  >2 publications with PKP3 and DSG2
 DSC3 antibody  >2 publications with PKP3 and DSC3
 DSC1 antibody  >2 publications with PKP3 and DSC1
 DSC2 antibody  >2 publications with PKP3 and DSC2
 ETV1 antibody  >1 publications with PKP3 and ETV1
 ZEB1 antibody  >1 publications with PKP3 and ZEB1
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Formation Of The Cornified Envelope Pathway antibodies  Formation Of The Cornified Envelope Pathway Diagram
 Keratinization Pathway antibodies  Keratinization Pathway Diagram
Diseases associated with anti-PKP3 antibodyOrgans/Tissues associated with anti-PKP3 antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >7 publications with PKP3 and Neoplasm Metastasis
 Respiratory Tract Diseases Antibodies  >4 publications with PKP3 and Respiratory Tract Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with PKP3 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >3 publications with PKP3 and Inflammation
 Prostatic Neoplasms Antibodies  >3 publications with PKP3 and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >2 publications with PKP3 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with PKP3 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with PKP3 and Liver Neoplasms
 Breast Neoplasms Antibodies  >1 publications with PKP3 and Breast Neoplasms
 Fibrosis Antibodies  >1 publications with PKP3 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >8 publications with PKP3 and Skin
 Lung Antibodies  >4 publications with PKP3 and Lung
 Embryonic Tissue Antibodies  >3 publications with PKP3 and Embryonic Tissue
 Prostate Antibodies  >3 publications with PKP3 and Prostate
 Liver Antibodies  >2 publications with PKP3 and Liver
 Connective Tissue Antibodies  >1 publications with PKP3 and Connective Tissue
 Brain Antibodies  >1 publications with PKP3 and Brain
 Heart Antibodies  >1 publications with PKP3 and Heart
 Stomach Antibodies  >1 publications with PKP3 and Stomach
 Bone Antibodies  >1 publications with PKP3 and Bone
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