AAA60067.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
platelet factor 4
NCBI Official Synonym Full Names
platelet factor 4 variant 1
NCBI Official Synonym Symbols
PF4A; CXCL4L1; CXCL4V1; PF4-ALT; SCYB4V1 [Similar Products]
NCBI Protein Information
platelet factor 4 variant; PF4alt; PF4var1; C-X-C motif chemokine 4; platelet factor 4, variant 1 (PF4-like)
UniProt Protein Name
Platelet factor 4 variant
UniProt Synonym Protein Names
C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1
UniProt Synonym Gene Names
UniProt Entry Name
PF4V_HUMAN
UniProt Comments for PF4V1
Function: Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro). Ref.5
Subunit structure: Homotetramer. Ref.6
Subcellular location: Secreted.
Post-translational modification: The N-terminal processed forms of platelet factor 4 variant seems to be produced by proteolytic cleavage. The most abundant form is Platelet factor 4 variant(5-74).
Miscellaneous: Binding to heparin is much weaker than in the close homolog PF4/CXCL4.
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Mass spectrometry: Molecular mass is 8250.9 Da from positions 31 - 104. Determined by ESI. Platelet factor 4 variant. Ref.5Molecular mass is 7877.7 Da from positions 34 - 104. Determined by ESI. Platelet factor 4 variant(4-74). Ref.5Molecular mass is 7805.8 Da from positions 35 - 104. Determined by ESI. Platelet factor 4 variant(5-74). Ref.5Molecular mass is 7678.6 Da from positions 36 - 104. Determined by ESI. Platelet factor 4 variant(6-74). Ref.5
Research Articles on PF4V1
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Pathways associated with anti-PF4V1 antibody
Diseases associated with anti-PF4V1 antibody
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