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anti-PRL antibody :: Mouse anti-Human Prolactin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS531244 anti-PRL antibody
Unit / Price
1 mg  /  $180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Prolactin (PRL), Monoclonal Antibody

 Also Known As   

Prolactin antibody

 Product Synonym Names    Monoclonal Prolactin; Anti-Prolactin; hPrl; Anti Prolactin; Prolactin
 Product Gene Name   

anti-PRL antibody

[Similar Products]
 Matching Pairs    Capture Antibody: Prolactin Clone #M94194 (MBS531244)
Detection Antibody: Prolactin Clone #M94193 (MBS530399)
Comments: Very good pair for ELISA
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176760
 3D Structure    ModBase 3D Structure for P01236
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 Clonality    Monoclonal
 Isotype    IgG
 Clone Number    M94194
 Host    Mouse
 Species Reactivity    Human
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 Form/Format    Chromatographically purified IgG fraction supplied in 50mM PBS buffer, pH 7.5 with 0.1% NaN3.
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 Biological Significance    Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of oxytocin, which stimulates lactogenesis, in preparation for the next feed.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Affinity Constant    7 x 10^9 l/mol
 Immunogen    Prolactin antibody was raised in mouse using human prolactin as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-PRL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PRL antibody

   Mouse monoclonal Prolactin antibody
 Product Categories/Family for anti-PRL antibody    Hormones & Steroids
 Applications Tested/Suitable for anti-PRL antibody   

User optimized

 Application Notes for anti-PRL antibody    Matched pair antibody available for Prolactin antibody: MBS530399
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NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
 NCBI GI #    254675133
 NCBI GeneID    5617
 NCBI Accession #    NP_001157030.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001163558.2 [Other Products]
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 UniProt Primary Accession #    P01236 [Other Products]
 UniProt Secondary Accession #    Q15199; Q92996 [Other Products]
 UniProt Related Accession #    P01236 [Other Products]
 Molecular Weight    25,876 Da [Similar Products]
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 NCBI Official Full Name    prolactin
 NCBI Official Synonym Full Names    prolactin
 NCBI Official Symbol    PRL [Similar Products]
 NCBI Protein Information    prolactin
 UniProt Protein Name    Prolactin
 Protein Family    Prolactin
 UniProt Gene Name    PRL [Similar Products]
 UniProt Synonym Gene Names    PRL [Similar Products]
 UniProt Entry Name    PRL_HUMAN
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 NCBI Summary for PRL    This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
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 UniProt Comments for PRL    prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Secreted; Secreted, signal peptide; Cytokine; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: protein binding; prolactin receptor binding; hormone activity

Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy
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 Research Articles on PRL    1. The prevalence and predictors of hyperprolactinemia in 178 patients with liver cirrhosis of different etio-logies, were investigated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PRL antibodyPathways associated with anti-PRL antibody
 Reference Product  PubMed Publications
 TRH antibody  >1759 publications with PRL and TRH
 PRLR antibody  >359 publications with PRL and PRLR
 JAK2 antibody  >191 publications with PRL and JAK2
 POU1F1 antibody  >141 publications with PRL and POU1F1
 STAT5A antibody  >81 publications with PRL and STAT5A
 STAT3 antibody  >63 publications with PRL and STAT3
 GHR antibody  >52 publications with PRL and GHR
 STAT5B antibody  >47 publications with PRL and STAT5B
 ESR1 antibody  >12 publications with PRL and ESR1
 BMP1 antibody  >2 publications with PRL and BMP1
 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 ErbB4 Signaling Events Pathway antibodies  ErbB4 Signaling Events Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Growth Hormone Receptor Signaling Pathway antibodies  Growth Hormone Receptor Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with anti-PRL antibodyOrgans/Tissues associated with anti-PRL antibody
 Disease Name  Pubmed Publications
 Pituitary Neoplasms Antibodies  >2039 publications with PRL and Pituitary Neoplasms
 Hyperprolactinemia Antibodies  >1532 publications with PRL and Hyperprolactinemia
 Adenoma Antibodies  >1500 publications with PRL and Adenoma
 Prolactinoma Antibodies  >686 publications with PRL and Prolactinoma
 Mental Disorders Antibodies  >609 publications with PRL and Mental Disorders
 Amenorrhea Antibodies  >428 publications with PRL and Amenorrhea
 Galactorrhea Antibodies  >318 publications with PRL and Galactorrhea
 Growth Hormone-Secreting Pituitary Adenoma Antibodies  >265 publications with PRL and Growth Hormone-Secreting Pituitary Adenoma
 Infertility, Female Antibodies  >241 publications with PRL and Infertility, Female
 Hypogonadism Antibodies  >209 publications with PRL and Hypogonadism
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5151 publications with PRL and Brain
 Pituitary Gland Antibodies  >3999 publications with PRL and Pituitary Gland
 Uterus Antibodies  >522 publications with PRL and Uterus
 Testis Antibodies  >500 publications with PRL and Testis
 Placenta Antibodies  >391 publications with PRL and Placenta
 Heart Antibodies  >210 publications with PRL and Heart
 Eye Antibodies  >196 publications with PRL and Eye
 Muscle Antibodies  >193 publications with PRL and Muscle
 Connective Tissue Antibodies  >121 publications with PRL and Connective Tissue
 Uncharacterized Tissue Antibodies  >1 publications with PRL and Uncharacterized Tissue
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