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Mouse anti-Human Prothrombin precursor Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS833279
Western Blot (WB)
Unit / Price
0.1 mL  /  $395 +1 FREE 8GB USB
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 Product Name   

Prothrombin precursor, Monoclonal Antibody

★Popular Item★
 Also Known As   

Prothrombin precursor antibody

 Product Synonym Names    Monoclonal Prothrombin precursor; Anti-Prothrombin precursor; F2; coagulation factor II (thrombin); Cf2; Cf-2; coagulation factor 2; coagulation factor 2 (thrombin); coagulation factor II; F2_BB; FII; Prothrombin; prothrombin B-chain; prothrombin precursor; PT; RP23-176N9.4; RPRGL2; serine protease; silk fibroin 2; THPH1; thrombin; thrombin B chain variant 1; vitamin K dependent serine protease
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    28H5
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Prothrombin precursor antibody was purified by ammonium sulfate precipitation
 Form/Format    Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
 Concentration    1mg/ml (lot specific)
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 Biological Significance    Prothrombin precursor is synthesized in liver as a precursor of prothrombin containing a signal sequence and a propeptide domain at the N-terminus. Before its secretion into plasma, this precursor undergoes several posttranslational modifications, including removal of signal sequence and propeptide domains, glycosylation, and gamma-glutamyl-carboxylation reaction. Prothrombin, cleaved by the prothrombinase enzyme complex that consists of serine protease factor Xa, cofactor Va, phospholipids and calcium, is converted to thrombin which converts fibrinogen into fibrin which in turn strengthens a protective clot. Activation of prothrombin is crucial in physiological and pathological coagulation. Various rare diseases involving prothrombin (e.g. hypoprothrombinemia) have been described.
 Immunogen    Prothrombin precursor antibody was raised in Mouse using a protein purified from Human plasma as the immunogen
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 Preparation and Storage    4 degree C shipping. Upon receipt store at at -20 degree C, avoid freeze/thaw cycles
 Other Notes    Small volumes of anti-Prothrombin precursor antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Prothrombin precursor antibody

   Mouse monoclonal Prothrombin precursor antibody
 Product Categories/Family for anti-Prothrombin precursor antibody    Cell Biology
 Applications Tested/Suitable for anti-Prothrombin precursor antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Prothrombin precursor antibody    WB: (0.5mg/ml)
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 Western Blot (WB) of anti-Prothrombin precursor antibody   
anti-Prothrombin precursor antibody Western Blot (WB) (WB) image
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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