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anti-H2-Q8 antibody :: Mouse anti-Mouse Qa-2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS602216 anti-H2-Q8 antibody
Unit / Price
0.5 mg  /  $520 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Qa-2 (H2-Q8), Monoclonal Antibody

 Also Known As   

Qa-2

 Product Synonym Names    Anti -Qa-2
 Product Gene Name   

anti-H2-Q8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    17 B1; 17
 3D Structure    ModBase 3D Structure for P14430
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 Clonality    Monoclonal
 Isotype    IgG2a,k
 Clone Number    5K44
 Host    Mouse
 Species Reactivity    Mouse
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 Specificity    Recognizes mouse Qa-2 alloantigen
 Purity/Purification    Purified
Purified
 Form/Format    Supplied as a liquid in 100mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
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 Immunogen    C3H.SW mouse skin graft and splenocytes
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-H2-Q8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-H2-Q8 antibody    Antibodies; Abs to Proteins
 Applications Tested/Suitable for anti-H2-Q8 antibody   

Flow Cytometry (FC/FACS)

 Application Notes for anti-H2-Q8 antibody    Suitable for use in Flow Cytometry and studies on complement-mediated cytotoxicity and modulation of Qa-2 expression from peripheral T-lymphocytes
Dilution: Flow Cytometry: 1ug/10e6 cells
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NCBI/Uniprot data below describe general gene information for H2-Q8. It may not necessarily be applicable to this product.
 NCBI GI #    1711287
 NCBI GeneID    15019
 NCBI Accession #    BAA14174.1 [Other Products]
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 UniProt Primary Accession #    P14430 [Other Products]
 UniProt Related Accession #    P14430 [Other Products]
 Molecular Weight    37,411 Da [Similar Products]
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 NCBI Official Full Name    Qa-2 cell surface antigen
 NCBI Official Synonym Full Names    histocompatibility 2, Q region locus 8
 NCBI Official Symbol    H2-Q8 [Similar Products]
 NCBI Official Synonym Symbols   
Qa8; Qa-2; Qa-8; H-2Q8; Ms10t; MMS10-T
[Similar Products]
 NCBI Protein Information    H-2 class I histocompatibility antigen, Q8 alpha chain; minisatellite 10t detected by probe MMS10
 UniProt Protein Name    H-2 class I histocompatibility antigen, Q8 alpha chain
 Protein Family    H-2 class I histocompatibility antigen
 UniProt Gene Name    H2-Q8 [Similar Products]
 UniProt Entry Name    HA18_MOUSE
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 UniProt Comments for H2-Q8    Function: Involved in the presentation of foreign antigens to the immune system.

Subunit structure: Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Belongs to the MHC class I family.Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
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 Research Articles on H2-Q8    1. During primary and secondary rejection of tumors, Q8 is recognized by cross-reactive antitumor cytotoxic T cells, has overlapping peptide-binding motifs, and is assembled via the transporter associated with the antigen processing pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-H2-Q8 antibodyOrgans/Tissues associated with anti-H2-Q8 antibody
 Products by Pathway  Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with H2-Q8 and Blood
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