Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow REXO2 rightarrow Monoclonal REXO2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Nuclear protein localization protein 4 homolog (NPLOC4) Recombinant Protein
 • Protease Activated Receptor 2 (PAR2) ELISA Kit
 • Membrane Cofactor Protein (MCP) ELISA Kit
 • ATP5D Antibody
 • Carboxypeptidase O (CPO) ELISA Kit
 • Alpha-1-B-Glycoprotein (a1BG) Antibody
 • X-ray repair complementing defective repair in Chinese hamst... ELISA Kit
 • B3GALT4 Antibody
 • Bacillolysin (npr) Recombinant Protein
 • VPS52 Antibody
 • IgG Antibody
 • ATP synthase subunit d, mitochondrial (ATP5H) Recombinant Protein
 • STOM Antibody
 • CD69 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-REXO2 antibody :: Mouse anti-Human REXO2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120308
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

REXO2, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human REXO2

 Product Synonym Names    Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae); RFN; SFN; CGI-114; MGC111570; DKFZP566E144
 Product Gene Name   

anti-REXO2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    607149
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    2276D6a
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-REXO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-REXO2 antibody

   Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.[supplied by OMIM] [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-REXO2 antibody   

Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

Section Bar
 Quality Control of anti-REXO2 antibody    Western blot analysis of immunized recombinant protein, using anti-REXO2 monoclonal antibody.
anti-REXO2 antibody Quality Control image
Section Bar
 Quality Control #2 of anti-REXO2 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-REXO2 antibody Quality Control #2 image
Section Bar
 Western Blot (WB) of anti-REXO2 antibody    Detection of REXO2 by Western blot.

Samples: Whole cell lysate from human HeLa (H, 25 ug), mouse NIH3T3 (M, 25 ug) and rat F2408 (R, 25 ug) cells. [Lot No. 2276D6a-1]

Predicted molecular weight: 26 kDa
anti-REXO2 antibody Western Blot (WB) (WB) image
Section Bar
 Immunocytochemistry (ICC) of anti-REXO2 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-REXO2 mAb. [Lot No. 2276D6a-1]
anti-REXO2 antibody Immunocytochemistry (ICC) (ICC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for REXO2. It may not necessarily be applicable to this product.
 NCBI GI #    224496105
 NCBI GeneID    25996
 NCBI Accession #    NP_056338.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_015523 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q32Q18; Q53FT1; Q6FIC6; Q9UFY7; B2R532 [Other Products]
 UniProt Related Accession #    Q9Y3B8 [Other Products]
 Molecular Weight    23,754 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens RNA exonuclease 2 (REXO2), mRNA
 NCBI Official Synonym Full Names    RNA exonuclease 2
 NCBI Official Symbol    REXO2 [Similar Products]
 NCBI Official Synonym Symbols   
RFN; SFN; REX2; CGI-114
[Similar Products]
 NCBI Protein Information    oligoribonuclease, mitochondrial; REX2, RNA exonuclease 2 homolog; small fragment nuclease
 UniProt Protein Name    Oligoribonuclease, mitochondrial
 UniProt Synonym Protein Names   
RNA exonuclease 2 homolog; Small fragment nuclease
 UniProt Gene Name    REXO2 [Similar Products]
 UniProt Entry Name    ORN_HUMAN
Section Bar
 NCBI Summary for REXO2    This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
Section Bar
 UniProt Comments for REXO2    REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2).

Protein type: Hydrolase; EC 3.1.-.-

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: focal adhesion; mitochondrion; mitochondrial matrix; nucleolus; mitochondrial intermembrane space; nucleus

Molecular Function: 3'-5'-exoribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity

Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process
Table BarTOPTable Bar
 Research Articles on REXO2    1. Loss of 14-3-3sigma sensitizes cells to UVB. After a transient cell cycle arrest, 14-3-3sigma-deficient cells die by undergoing mitotic catastrophe.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-REXO2 antibody
 Products by Pathway  Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions