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anti-RPA3 antibody :: Mouse anti-Human, Mouse RPA3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS245085
Immunohistochemistry (IHC)
Unit / Price
0.05 mL  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RPA3, Monoclonal Antibody

 Also Known As   

Mouse Monoclonal [clone 111] (IgG1) to Human RPA3

 Product Synonym Names    Anti-RPA3 Antibody (clone 111) IHC-plus; RPA3; REPA3; Replication factor A protein 3; Replication protein A3 (14kD); Replication protein A3; 14kDa; RF-A protein 3; RP-A p14; RPA14; Human RPA3
 Product Gene Name   

anti-RPA3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    179837
 3D Structure    ModBase 3D Structure for P35244
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    111
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Specificity    Full-length human RPA-14 expressed in E Coli.
 Purity/Purification    Protein G Purified
 Form/Format    PBS. Sourced in TCS.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Recombinant human RPA3.
 Immunogen Type    Recombinant protein
 Immunogen    RPA3 antibody was raised against recombinant human RPA3.
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 Preparation and Storage    Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of anti-RPA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RPA3 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)

 Application Notes for anti-RPA3 antibody    IHC-P (5 ug/ml), IP, WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-RPA3 antibody    Anti-RPA3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-RPA3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for RPA3. It may not necessarily be applicable to this product.
 NCBI GI #    4506587
 NCBI GeneID    6119
 NCBI Accession #    NP_002938.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002947.3 [Other Products]
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 UniProt Primary Accession #    P35244 [Other Products]
 UniProt Secondary Accession #    Q549U6 [Other Products]
 UniProt Related Accession #    P35244 [Other Products]
 Molecular Weight    13,569 Da
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 NCBI Official Full Name    replication protein A 14 kDa subunit
 NCBI Official Synonym Full Names    replication protein A3, 14kDa
 NCBI Official Symbol    RPA3 [Similar Products]
 NCBI Official Synonym Symbols   
REPA3
[Similar Products]
 NCBI Protein Information    replication protein A 14 kDa subunit; RP-A p14; RF-A protein 3; replication factor A protein 3
 UniProt Protein Name    Replication protein A 14 kDa subunit
 UniProt Synonym Protein Names   
Replication factor A protein 3; RF-A protein 3
 Protein Family    Replication protein
 UniProt Gene Name    RPA3 [Similar Products]
 UniProt Synonym Gene Names    REPA3; RPA14; RP-A p14; RF-A protein 3 [Similar Products]
 UniProt Entry Name    RFA3_HUMAN
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 UniProt Comments for RPA3    RPA3: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: nucleoplasm; DNA replication factor A complex

Molecular Function: protein binding; damaged DNA binding; single-stranded DNA binding

Biological Process: mismatch repair; regulation of mitotic cell cycle; DNA strand elongation during DNA replication; DNA repair; double-strand break repair via homologous recombination; regulation of cell proliferation; telomere maintenance via semi-conservative replication; DNA recombinase assembly; nucleotide-excision repair; base-excision repair; transcription-coupled nucleotide-excision repair; double-strand break repair; telomere maintenance via recombination; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA gap filling; mitotic cell cycle; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle
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 Research Articles on RPA3    1. The allele "T" of rs6947203 in the RPA3 gene acts as a protective allele in glioma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RPA3 antibodyPathways associated with anti-RPA3 antibody
 Reference Product  PubMed Publications
 RPA2 antibody  >38 publications with RPA3 and RPA2
 RPA1 antibody  >28 publications with RPA3 and RPA1
 RPA4 antibody  >6 publications with RPA3 and RPA4
 PCNA antibody  >3 publications with RPA3 and PCNA
 MCM4 antibody  >1 publications with RPA3 and MCM4
 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Assembly Of The RAD51-ssDNA Nucleoprotein Complex Pathway antibodies  Assembly Of The RAD51-ssDNA Nucleoprotein Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chromosome Maintenance Pathway antibodies  Chromosome Maintenance Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
Diseases associated with anti-RPA3 antibodyOrgans/Tissues associated with anti-RPA3 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with RPA3 and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with RPA3 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with RPA3 and Neoplasm Metastasis
 Precancerous Conditions Antibodies  >1 publications with RPA3 and Precancerous Conditions
 Breast Neoplasms Antibodies  >1 publications with RPA3 and Breast Neoplasms
 Weight Loss Antibodies  >1 publications with RPA3 and Weight Loss
 Kidney Diseases Antibodies  >1 publications with RPA3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with RPA3 and Brain
 Blood Antibodies  >3 publications with RPA3 and Blood
 Muscle Antibodies  >2 publications with RPA3 and Muscle
 Heart Antibodies  >2 publications with RPA3 and Heart
 Lymph Antibodies  >1 publications with RPA3 and Lymph
 Skin Antibodies  >1 publications with RPA3 and Skin
 Lymph Node Antibodies  >1 publications with RPA3 and Lymph Node
 Kidney Antibodies  >1 publications with RPA3 and Kidney
 Lung Antibodies  >1 publications with RPA3 and Lung
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