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anti-SCML2 antibody :: Mouse anti-Human SCML2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120034
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SCML2, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human SCML2

 Product Synonym Names    Homo sapiens sex comb on midleg-like 2 (Drosophila) (SCML2), mRNA
 Product Gene Name   

anti-SCML2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300208
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    SCMAD14A
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-SCML2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SCML2 antibody

   Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). [UniProtKB Function]
 Applications Tested/Suitable for anti-SCML2 antibody   

Dot Blot (DB), Western Blot (WB)

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 Quality Control of anti-SCML2 antibody    Western blot analysis of immunized recombinant protein, using anti-SCML2 monoclonal antibody.
anti-SCML2 antibody Quality Control image
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 Quality Control #2 of anti-SCML2 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-SCML2 antibody Quality Control #2 image
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 Western Blot (WB) of anti-SCML2 antibody    Detection of SCML2 by Western blot.

Samples: Whole cell lysate from human HeLa (H, 25 ug), mouse NIH3T3 (M, 25 ug) and rat F2408 (R, 25 ug) cells. [Lot No. SCMAD14A-3]

Predicted molecular weight: 77 kDa
anti-SCML2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SCML2. It may not necessarily be applicable to this product.
 NCBI GI #    193794845
 NCBI GeneID    10389
 NCBI Accession #    NP_006080.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006089 [Other Products]
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 UniProt Secondary Accession #    Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5 [Other Products]
 UniProt Related Accession #    Q9UQR0 [Other Products]
 Molecular Weight    15,471 Da
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 NCBI Official Full Name    Homo sapiens sex comb on midleg-like 2 (Drosophila) (SCML2), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    sex comb on midleg-like 2 (Drosophila)
 NCBI Official Symbol    SCML2 [Similar Products]
 NCBI Protein Information    sex comb on midleg-like protein 2
 UniProt Protein Name    Sex comb on midleg-like protein 2
 Protein Family    Sex comb on midleg-like protein
 UniProt Gene Name    SCML2 [Similar Products]
 UniProt Entry Name    SCML2_HUMAN
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 NCBI Summary for SCML2    This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010]
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 UniProt Comments for SCML2    SCML2: a protein of unknown function. Contains a SAM (sterile alpha motif) and two MBT domains.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: PcG protein complex; nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: anatomical structure morphogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent
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 Research Articles on SCML2    1. Because PRC1 complexes localize to the promoters of a specific subset of developmental genes in vivo, the SLED domain of Scml2 may provide an important link connecting the PRC1 complexes to their target genes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SCML2 antibodyDiseases associated with anti-SCML2 antibody
 Reference Product  PubMed Publications
 PCGF2 antibody  >1 publications with SCML2 and PCGF2
 BMI1 antibody  >1 publications with SCML2 and BMI1
 RNF2 antibody  >1 publications with SCML2 and RNF2
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with SCML2 and Nervous System Diseases
Organs/Tissues associated with anti-SCML2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with SCML2 and Brain
 Bone Marrow Antibodies  >1 publications with SCML2 and Bone Marrow
 Testis Antibodies  >1 publications with SCML2 and Testis
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