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anti-SNAPC4 antibody :: Mouse anti-Human SNAPC4 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120035
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SNAPC4, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human SNAPC4

 Product Synonym Names    small nuclear RNA activating complex, polypeptide 4,190kDa (SNAPC4); SNAP190; FLJ13451; PTFalpha
 Product Gene Name   

anti-SNAPC4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602777
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    SNAAD17A
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-SNAPC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SNAPC4 antibody

   Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box{EC1,EC2}. [UniProtKB Function]
 Applications Tested/Suitable for anti-SNAPC4 antibody   

ELISA (EIA), Western Blot (WB)

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 Quality Control of anti-SNAPC4 antibody    Western blot analysis of immunized recombinant protein, using anti-SNAPC4 monoclonal antibody.
anti-SNAPC4 antibody Quality Control image
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 Quality Control #2 of anti-SNAPC4 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-SNAPC4 antibody Quality Control #2 image
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 Western Blot (WB) of anti-SNAPC4 antibody    Detection of human SNAPC4 by Western blot.

Samples: Whole cell lysate (50 ug) from HeLa cells. [Lot No. SNAAD17A-1]

Predicted molecular weight: 159 kDa
anti-SNAPC4 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SNAPC4. It may not necessarily be applicable to this product.
 NCBI GI #    92859677
 NCBI GeneID    6621
 NCBI Accession #    NP_003077.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003086 [Other Products]
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 UniProt Secondary Accession #    Q9Y6P7 [Other Products]
 UniProt Related Accession #    Q5SXM2 [Other Products]
 Molecular Weight    159,433 Da
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 NCBI Official Full Name    Homo sapiens small nuclear RNA activating complex, polypeptide 4, 190kDa (SNAPC4), mRNA
 NCBI Official Synonym Full Names    small nuclear RNA activating complex, polypeptide 4, 190kDa
 NCBI Official Symbol    SNAPC4 [Similar Products]
 NCBI Official Synonym Symbols   
SNAP190; PTFalpha
[Similar Products]
 NCBI Protein Information    snRNA-activating protein complex subunit 4; PSE-binding factor subunit alpha; PTF subunit alpha; SNAPC4; SNAPc 190 kDa subunit; SNAPc subunit 4; proximal sequence element-binding transcription factor subunit alpha; small nuclear RNA activating complex, polypeptide 4, 190kD; snRNA-activating protein complex 190 kDa subunit
 UniProt Protein Name    snRNA-activating protein complex subunit 4
 UniProt Synonym Protein Names   
Proximal sequence element-binding transcription factor subunit alpha; PSE-binding factor subunit alpha; PTF subunit alpha; snRNA-activating protein complex 190 kDa subunit; SNAPc 190 kDa subunit
 Protein Family    snRNA-activating protein complex
 UniProt Gene Name    SNAPC4 [Similar Products]
 UniProt Entry Name    SNPC4_HUMAN
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 UniProt Comments for SNAPC4    SNAP190: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: nucleoplasm; snRNA-activating protein complex; nucleus

Molecular Function: DNA binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; snRNA transcription; snRNA transcription from RNA polymerase II promoter; gene expression; snRNA transcription from RNA polymerase III promoter
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 Research Articles on SNAPC4    1. Our study confirmed that an SNP rs11145835 in 9q34.3 that harbors CARD9 and SNAPC4 is associated with ankylosing spondylitis in a Chinese Han population
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SNAPC4 antibodyPathways associated with anti-SNAPC4 antibody
 Reference Product  PubMed Publications
 SNAPC1 antibody  >3 publications with SNAPC4 and SNAPC1
 TBP antibody  >2 publications with SNAPC4 and TBP
 POU2F1 antibody  >2 publications with SNAPC4 and POU2F1
 SNAPC2 antibody  >2 publications with SNAPC4 and SNAPC2
 SNAPC5 antibody  >1 publications with SNAPC4 and SNAPC5
 SNAPC3 antibody  >1 publications with SNAPC4 and SNAPC3
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Initiation Pathway antibodies  RNA Polymerase III Transcription Initiation Pathway Diagram
 RNA Polymerase III Transcription Initiation From Type 3 Promoter Pathway antibodies  RNA Polymerase III Transcription Initiation From Type 3 Promoter Pathway Diagram
Diseases associated with anti-SNAPC4 antibodyOrgans/Tissues associated with anti-SNAPC4 antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with SNAPC4 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >1 publications with SNAPC4 and Pancreas
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