Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow SRD5A1 rightarrow Monoclonal SRD5A1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • SNAP-25 Antibody
 • Proopiomelanocortin (POMC) ELISA Kit
 • 3-oxo-5-beta-steroid 4-dehydrogenase (AKR1D1) Recombinant Protein
 • Triiodothyronine (T3) ELISA Kit
 • Cross Linked C-Telopeptide Of Type II Collagen (CTXII) ELISA Kit
 • Serum Amyloid A (SAA) ELISA Kit
 • a-Chymotrypsinogen A Antibody
 • SESN3 ELISA Kit
 • S100A4 - FSP1 Antibody
 • MMP2 Antibody
 • ADCY2 ELISA Kit
 • GAD2-GAD65 Antibody
 • INTEGRIN ALPHA V BETA 5 (ITGB5) Antibody
 • NADP Biochemical
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-SRD5A1 antibody :: Mouse anti-Human SRD5A1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2549145
Western Blot (WB)
Unit / Price
0.06 mL  /  $220 +1 FREE 8GB USB
0.12 mL  /  $290 +1 FREE 8GB USB
0.2 mL  /  $435 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SRD5A1, Monoclonal Antibody

 Also Known As   

SRD5A1 Monoclonal Antibody

 Product Synonym Names    S5AR 1; SR type 1; SRD5A1; Steroid 5 alpha reductase 1
 Product Gene Name   

anti-SRD5A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    M32313 mRNA
 3D Structure    ModBase 3D Structure for P18405
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1D5D8
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Purity/Purification    Protein G Purification
 Concentration    1mg/mL (lot specific)
Section Bar
 Immunogen    Fusion Protein of SRD5A1
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, PH7.3
 Conjugation    Unconjugated
Section Bar
 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SRD5A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-SRD5A1 antibody

   Steroid 5-alpha-reductase (SRD5A1) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). SRD5A1 is a minor component of the reductase activity in prostate although the gene was originally cloned from prostate. On the other hand,  SRD5A1 appears to be the predominant isozyme of steroid 5-alpha-reductase in the scalp and elsewhere in the skin.
 Applications Tested/Suitable for anti-SRD5A1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-SRD5A1 antibody    WB: 1:500-1:5000
IHC: 1:50-1:500
IF: 1:50-1:500
Section Bar
 Western Blot (WB) of anti-SRD5A1 antibody    Western Blot analysis of Human testis tissue using SRD5A1 Monoclonal Antibody at dilution of 1:1000
anti-SRD5A1 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for SRD5A1. It may not necessarily be applicable to this product.
 NCBI GI #    13937854
 NCBI GeneID    6715
 NCBI Accession #    BC007033 [Other Products]
Section Bar
 UniProt Primary Accession #    P18405 [Other Products]
 UniProt Secondary Accession #    Q9UHY4; Q9UP36; Q9UP37; B2R7Q1 [Other Products]
 UniProt Related Accession #    P18405 [Other Products]
 Molecular Weight    32kDa
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA
 NCBI Official Synonym Full Names    steroid 5 alpha-reductase 1
 NCBI Official Symbol    SRD5A1 [Similar Products]
 NCBI Official Synonym Symbols   
S5AR 1
[Similar Products]
 NCBI Protein Information    3-oxo-5-alpha-steroid 4-dehydrogenase 1
 UniProt Protein Name    3-oxo-5-alpha-steroid 4-dehydrogenase 1
 UniProt Synonym Protein Names   
SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
 Protein Family    3-oxo-5-alpha-steroid 4-dehydrogenase
 UniProt Gene Name    SRD5A1 [Similar Products]
 UniProt Synonym Gene Names    S5AR 1 [Similar Products]
Section Bar
 NCBI Summary for SRD5A1    Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
Section Bar
 UniProt Comments for SRD5A1    SRD5A1: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Belongs to the steroid 5-alpha reductase family.

Protein type: EC 1.3.1.22; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Chromosomal Location of Human Ortholog: 5p15.31

Cellular Component: cell soma; endoplasmic reticulum membrane; integral component of membrane; myelin sheath; perinuclear region of cytoplasm

Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity; amide binding; cholestenone 5-alpha-reductase activity; electron transfer activity

Biological Process: androgen biosynthetic process; cell differentiation; cellular response to insulin stimulus; cellular response to starvation; cerebral cortex development; circadian sleep/wake cycle, REM sleep; diterpenoid metabolic process; female genitalia development; hippocampus development; hypothalamus development; liver development; male genitalia development; male gonad development; pituitary gland development; progesterone metabolic process; response to drug; response to estrogen; response to follicle-stimulating hormone stimulus; response to muscle activity; serotonin metabolic process; sex determination; spinal cord development; thalamus development; urogenital system development
Table BarTOPTable Bar
 Research Articles on SRD5A1    1. Findings suggest that 5alpha-reductases (5-AR) isoenzymes could be explored as a therapeutic target for urothelial bladder cancer (UBC) with 5alpha-reductase inhibitors (5-ARI).
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-SRD5A1 antibodyDiseases associated with anti-SRD5A1 antibody
 Products by Pathway  Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Steroid Hormones And Vitamin D Pathway antibodies  Metabolism Of Steroid Hormones And Vitamin D Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >28 publications with SRD5A1 and Neoplasms
 Genital Diseases, Male Antibodies  >21 publications with SRD5A1 and Genital Diseases, Male
 Prostatic Neoplasms Antibodies  >19 publications with SRD5A1 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >5 publications with SRD5A1 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >5 publications with SRD5A1 and Breast Neoplasms
 Hyperplasia Antibodies  >4 publications with SRD5A1 and Hyperplasia
 Urogenital Abnormalities Antibodies  >4 publications with SRD5A1 and Urogenital Abnormalities
 Neoplasm Metastasis Antibodies  >4 publications with SRD5A1 and Neoplasm Metastasis
 Carcinoma Antibodies  >3 publications with SRD5A1 and Carcinoma
 Disorders of Sex Development Antibodies  >3 publications with SRD5A1 and Disorders of Sex Development
Organs/Tissues associated with anti-SRD5A1 antibody
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >27 publications with SRD5A1 and Prostate
 Blood Antibodies  >20 publications with SRD5A1 and Blood
 Brain Antibodies  >8 publications with SRD5A1 and Brain
 Muscle Antibodies  >7 publications with SRD5A1 and Muscle
 Liver Antibodies  >6 publications with SRD5A1 and Liver
 Testis Antibodies  >6 publications with SRD5A1 and Testis
 Ovary Antibodies  >6 publications with SRD5A1 and Ovary
 Uterus Antibodies  >5 publications with SRD5A1 and Uterus
 Bone Antibodies  >5 publications with SRD5A1 and Bone
 Vascular Antibodies  >4 publications with SRD5A1 and Vascular
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions