NP_032434.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
80,598 Da
NCBI Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
NCBI Official Synonym Full Names
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
NCBI Protein Information
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; B5; STT3-A; integral membrane protein 1; intergral membrane protein 1; oligosaccharyl transferase subunit STT3A
UniProt Protein Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
UniProt Synonym Protein Names
B5; Integral membrane protein 1
UniProt Synonym Gene Names
UniProt Entry Name
STT3A_MOUSE
UniProt Comments for STT3A
ITM1: Catalytic component of oligosaccharyltransferase (OST) oligosaccharyltransferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X- Ser/Thr consensus motif in nascent polypeptide chains. N- glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A. Belongs to the STT3 family.
Protein type: Transferase; Endoplasmic reticulum; EC 2.4.99.18; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: membrane; endoplasmic reticulum; integral to membrane
Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; oligosaccharyl transferase activity
Biological Process: co-translational protein modification; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine
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Pathways associated with anti-STT3A antibody
Diseases associated with anti-STT3A antibody
Organs/Tissues associated with anti-STT3A antibody
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