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anti-SFTPD antibody :: Mouse SURFACTANT PROTEIN D Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS219620
Testing Data
Unit / Price
0.25 mg  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SURFACTANT PROTEIN D (SFTPD), Monoclonal Antibody

★Popular Item★
 Also Known As   

MOUSE ANTI PIG SURFACTANT PROTEIN D

 Product Gene Name   

anti-SFTPD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9N1X4
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1.7
 Host    Mouse
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 Specificity    This item detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.
 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1.0mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
Preparation
 Immunogen    Purified porcine surfactant protein D
Histology Positive Control Tissue
 Target Species    Pig
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SFTPD antibody

   MBS219620 detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.
 Applications Tested/Suitable for anti-SFTPD antibody   

Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB)

 Application Notes for anti-SFTPD antibody    Western Blot: This item detects a band of approximately 138kDa.
Immunohistology - Frozen: Minimum Dilution: 1ug/ml
Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

TRIS/EDTA buffer pH8.0 is recommended for this purpose.
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 Testing Data of anti-SFTPD antibody    Staining of frozen pig lung with Mouse anti pig Surfactant Protein D
anti-SFTPD antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.
 NCBI GI #    47523028
 NCBI GeneID    397198
 NCBI Accession #    NP_999275.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_214110.1 [Other Products]
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 UniProt Primary Accession #    Q9N1X4 [Other Products]
 UniProt Related Accession #    Q9N1X4 [Other Products]
 Molecular Weight    37,986 Da [Similar Products]
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 NCBI Official Full Name    pulmonary surfactant-associated protein D
 NCBI Official Symbol    SFTPD [Similar Products]
 NCBI Official Synonym Symbols   
SP-D; PSP-D
[Similar Products]
 NCBI Protein Information    pulmonary surfactant-associated protein D; lung surfactant protein D; surfactant, pulmonary-associated protein D
 UniProt Protein Name    Pulmonary surfactant-associated protein D
 UniProt Synonym Protein Names   
Lung surfactant protein D
 Protein Family    Pulmonary surfactant-associated protein
 UniProt Gene Name    SFTPD [Similar Products]
 UniProt Synonym Gene Names    PSP-D; SP-D [Similar Products]
 UniProt Entry Name    SFTPD_PIG
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 UniProt Comments for SFTPD    Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties ().
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 Research Articles on SFTPD    1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SFTPD antibodyPathways associated with anti-SFTPD antibody
 Reference Product  PubMed Publications
 SFTPB antibody  >7 publications with SFTPD and SFTPB
 SFTPA antibody  >6 publications with SFTPD and SFTPA
 SFTPC antibody  >5 publications with SFTPD and SFTPC
 SCGB1A1 antibody  >2 publications with SFTPD and SCGB1A1
 SLC34A2 antibody  >1 publications with SFTPD and SLC34A2
 Products by Pathway  Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
Diseases associated with anti-SFTPD antibodyOrgans/Tissues associated with anti-SFTPD antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >27 publications with SFTPD and Lung Diseases
 Respiratory Tract Diseases Antibodies  >27 publications with SFTPD and Respiratory Tract Diseases
 Inflammation Antibodies  >16 publications with SFTPD and Inflammation
 Lung Injury Antibodies  >9 publications with SFTPD and Lung Injury
 Pneumonia Antibodies  >5 publications with SFTPD and Pneumonia
 Lung Neoplasms Antibodies  >4 publications with SFTPD and Lung Neoplasms
 Respiratory Hypersensitivity Antibodies  >3 publications with SFTPD and Respiratory Hypersensitivity
 Cardiovascular Diseases Antibodies  >3 publications with SFTPD and Cardiovascular Diseases
 Premature Birth Antibodies  >3 publications with SFTPD and Premature Birth
 Respiratory Distress Syndrome, Adult Antibodies  >2 publications with SFTPD and Respiratory Distress Syndrome, Adult
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >34 publications with SFTPD and Lung
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