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anti-stx2A antibody :: Mouse anti-Human Shiga Toxin A subunit Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS680061 anti-stx2A antibody
Unit / Price
0.1 mg  /  $380 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Shiga Toxin A subunit (stx2A), Monoclonal Antibody

 Also Known As   

mAb to Shiga Toxin A subunit

 Product Synonym Names    MAb to A subunit Shiga Toxin; Shiga toxin Stx2A Monoclonal Antibody; SLT-2 A subunit; SLT-2a; SLT-IIa; Verocytotoxin 2 subunit A; Verotoxin 2 subunit A; rRNA N-glycosidase 2; stxA2; stx2A
 Product Gene Name   

anti-stx2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    198-212
 Chromosome Location    NC_002655.2 (1352290..1353249). Location: lab host: Escherichia coli C600
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1C6A6G9
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Shiga Toxin A subunit (stxA2)
 Form/Format    Affinity Purified
 Concentration    1.0 mg/ml in PBS pH 7.2 (lot specific)
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 Immunogen    Peptide
 Reconstitution    Add 100ul of ddH2O to the tube containing antibody and mix to dissolve
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 Preparation and Storage    Store at -20 degree C until use. Upon reconstitution, 4 degree C or sub-aliquot and -20 degree C.
 Other Notes    Small volumes of anti-stx2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-stx2A antibody

   mAb to Stx A
A is a 35 kDa subunit of Shiga Toxin

The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
 Applications Tested/Suitable for anti-stx2A antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-stx2A antibody    ELISA (EIA): Positive
Western Blot: Yes - dilute at 1:1000
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NCBI/Uniprot data below describe general gene information for stx2A. It may not necessarily be applicable to this product.
 NCBI GI #    15800960
 NCBI GeneID    959106
 NCBI Accession #    NP_286976 [Other Products]
 NCBI GenBank Nucleotide #    NC_002655.2 [Other Products]
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 NCBI Official Full Name    shiga-like toxin II A subunit encoded by bacteriophage BP-933W
 NCBI Official Symbol    stx2A [Similar Products]
 NCBI Protein Information    shiga-like toxin II A subunit encoded by bacteriophage BP-933W
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-stx2A antibody
 Products by Pathway  Pathway Diagram
 EHEC Pathogenicity Signature, Shiga Toxin Pathway antibodies  EHEC Pathogenicity Signature, Shiga Toxin Pathway Diagram
 EHEC Pathogenicity Signature, Shiga Toxin Pathway antibodies  EHEC Pathogenicity Signature, Shiga Toxin Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
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