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Mouse anti-Human Spectrin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS370107
Unit / Price
5 Control Slides  /  $130 +1 FREE 8GB USB
3 ml (Prediluted)  /  $185 +1 FREE 8GB USB
0.1 mL (Concentrate)  /  $190 +1 FREE 8GB USB
7 ml (Prediluted)  /  $275 +1 FREE 8GB USB
0.5 mL (Concentrate)  /  $280 +1 FREE 8GB USB
1 mL (Concentrate)  /  $450 +1 FREE 8GB USB
15 ml (Prediluted)  /  $450 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Spectrin, Monoclonal Antibody

★Popular Item★
 Also Known As   

Spectrin

 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2b/K
 Clone Number    RBC2/3D5
 Host    Mouse
 Species Reactivity    Human
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 Form/Format    Anti-Spectrin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
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 Control    Bone Marrow
 Localization    Membranous
 Reactivity Note    Paraffin, Frozen
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 Preparation and Storage    Store at 2 to 8 degree C in the dark.

Stability: 3 years
 Other Notes    Small volumes of anti-Spectrin antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Spectrin antibody

   Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh. Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of Erythroid Leukemias.
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 Dilution Information of anti-Spectrin antibody    anti-Spectrin antibody Dilution Information image
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 Immunohistochemistry (IHC) of anti-Spectrin antibody    Recommended Immunohistochemical Protocol

Pretreatment:
1. Cut and mount 3-4 micron formalin-fixed paraffin-embedded tissues on positive charged slides.
2. Air dry for 2 hours at 58 C.
3. Oeparaffinize, dehydrate and rehydrate tissues.
4. Subject tissues to heat epitope retrieval using a suitable retrieval solution such as ImmunoDNA Retriever with Citrate or EDTA.
5. Any of three heating methods may be used:
a. Electric Pressure Cooker
Place standoff rack at base of pressure cooker. Add 1 -2 inches of distilled water to the pressure cooker and turn heat to high, and incubate for 15 minutes. Open and immediately transfer slides to room temperature.
b. Water Bath Method
Place tissues/slides in a pre-warmed staining dish or coplin jar containing the ImmunoDNA Retriever with Citrate or EDTA in a water bath set at 95-99 C.lncubate for 30-60 minutes.
c. Conventional Steamer Method
Place tissues/slides in a pre-warmed staining dish or coplin jar containing the ImmunoDNA Retriever with Citrate or EDTA in a Steamer, cover and steam for 30-60 minutes.
6. After heat treatment, transfer slides in ImmunoDNA Retriever with Citrate or EDTA to room temperature and let stand for 15-20 minutes.
7. Wash slides with IHC wash buffer or 01 water.
8. Continue IHC staining protocol.
anti-Spectrin antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for Spectrin. It may not necessarily be applicable to this product.
 NCBI GI #    326432335
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 NCBI Official Full Name    spectrin
 Protein Family    Spectrin
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Spectrin antibodyPathways associated with anti-Spectrin antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with Spectrin and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-Spectrin antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Spectrin and Bone
 Connective Tissue Antibodies  >4 publications with Spectrin and Connective Tissue
 Heart Antibodies  >3 publications with Spectrin and Heart
 Muscle Antibodies  >3 publications with Spectrin and Muscle
 Brain Antibodies  >3 publications with Spectrin and Brain
 Vascular Antibodies  >2 publications with Spectrin and Vascular
 Embryonic Tissue Antibodies  >2 publications with Spectrin and Embryonic Tissue
 Ear Antibodies  >1 publications with Spectrin and Ear
 Kidney Antibodies  >1 publications with Spectrin and Kidney
 Umbilical Cord Antibodies  >1 publications with Spectrin and Umbilical Cord
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