NM_015136.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
NCBI Official Full Name
Stabilin-1
UniProt Protein Name
Stabilin-1
UniProt Synonym Protein Names
Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1; FEEL-1; MS-1 antigen
UniProt Synonym Gene Names
UniProt Comments for STAB1
STAB1: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: low-density lipoprotein binding; low-density lipoprotein receptor activity; protein binding; scavenger receptor activity
Biological Process: cell-cell signaling; defense response to bacterium; negative regulation of angiogenesis; receptor-mediated endocytosis
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Products associated with anti-STAB1 antibody
Pathways associated with anti-STAB1 antibody
Diseases associated with anti-STAB1 antibody
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