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anti-MAST1 antibody :: Mouse anti-Rat Syntrophin-Associated Serine/Threonine Kinase 124 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS602053 anti-MAST1 antibody
Unit / Price
0.1 mg  /  $910 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Syntrophin-Associated Serine/Threonine Kinase 124 (MAST1), Monoclonal Antibody

 Also Known As   

Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)

 Product Synonym Names    Anti -Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)
 Product Gene Name   

anti-MAST1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    chromosome: 19; Location: 19q11
 3D Structure    ModBase 3D Structure for Q810W7
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    6A623
 Host    Mouse
 Species Reactivity    Rat
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 Specificity    Recognizes rat SAST-124.
 Purity/Purification    Affinity Purified
Purified IgG
 Form/Format    Supplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA.
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 Immunogen    Rat Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-MAST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MAST1 antibody

   Syntrophin-associated serine/threonine kinase-124 (SAST-124) is a signalling molecule belonging to the microtubule-associated serine/threonine kinases. They have a unique structural feature with a serine/threonine kinase domain and a postsynaptic density protein-95/discs large/zona occludens-1 domain. SAST-124 is a signalling protein that binds to syntrophin, an adaptor protein that connects signalling molecules to the dystrophin-associated protein complex. SAST-124 is expressed in neurons of the subventricular zone and granule cells of the olfactory bulb, Islands of Calleja, hippocampal dentate gyrus and cerebellum. SAST-124 is selectively expressed in the nuclei of neurons. SAST-124 has a role in transcriptional regulation in the adult stem cells and their progeny cells in brain. SAST-124 is also located in glia-like small cells of the corpus callosum and the trigeminal ganglion cells indicating a function other than transcriptional regulation.
 Product Categories/Family for anti-MAST1 antibody    Antibodies; Abs to Protein Kinases
 Applications Tested/Suitable for anti-MAST1 antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

 Application Notes for anti-MAST1 antibody    Suitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry.
Dilution: Western Blot: 1:10
Immunoprecipitation: 1:10
Immunohistochemistry: frozen sections
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NCBI/Uniprot data below describe general gene information for MAST1. It may not necessarily be applicable to this product.
 NCBI GI #    29373055
 NCBI GeneID    353118
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 UniProt Primary Accession #    Q810W7 [Other Products]
 UniProt Secondary Accession #    Q810W8 [Other Products]
 UniProt Related Accession #    Q810W7 [Other Products]
 Molecular Weight    171,028 Da [Similar Products]
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 NCBI Official Full Name    syntrophin-associated serine/threonine kinase SAST124
 NCBI Official Synonym Full Names    microtubule associated serine/threonine kinase 1
 NCBI Official Symbol    MAST1 [Similar Products]
 NCBI Official Synonym Symbols   
Sast; MAST1
[Similar Products]
 NCBI Protein Information    microtubule-associated serine/threonine-protein kinase 1; syntrophin associated serine/threonine kinase; syntrophin-associated serine/threonine-protein kinase
 UniProt Protein Name    Microtubule-associated serine/threonine-protein kinase 1
 UniProt Synonym Protein Names   
Syntrophin-associated serine/threonine-protein kinase
 Protein Family    Microtubule-associated serine/threonine-protein kinase
 UniProt Gene Name    Mast1 [Similar Products]
 UniProt Synonym Gene Names    Sast [Similar Products]
 UniProt Entry Name    MAST1_RAT
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 NCBI Summary for MAST1    interacts with syntrophin on the cell surface [RGD]
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 UniProt Comments for MAST1    MAST1: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, AGC; AGC group; MAST family

Cellular Component: cytoskeleton; membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: protein serine/threonine kinase activity; magnesium ion binding; ATP binding

Biological Process: cytoskeleton organization and biogenesis; protein amino acid phosphorylation
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 Research Articles on MAST1    1. MAST1 expression patterns are evident in the hippocampus, cerebellum, 3rd ventricle and cerebral cortex of rats.
2. Syntrophin-associated serine/threonine kinase-124 (Sast124) is selectively localized in the nuclei of brain neurons and is distinct from syntrophin-associated serine/threonine kinase-170, which interacts with syntrophin on the cell surface.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-MAST1 antibodyOrgans/Tissues associated with anti-MAST1 antibody
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with MAST1 and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with MAST1 and Brain
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