AAK13473
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,688 Da
NCBI Official Full Name
transducin beta-like 1
NCBI Official Synonym Full Names
transducin beta like 1 Y-linked
NCBI Official Synonym Symbols
NCBI Protein Information
F-box-like/WD repeat-containing protein TBL1Y
UniProt Protein Name
F-box-like/WD repeat-containing protein TBL1Y
UniProt Synonym Protein Names
Transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked
UniProt Synonym Gene Names
NCBI Summary for TBL1Y
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for TBL1Y
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange ().
Research Articles on TBL1Y
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Products associated with anti-TBL1Y antibody
Pathways associated with anti-TBL1Y antibody
Diseases associated with anti-TBL1Y antibody
Organs/Tissues associated with anti-TBL1Y antibody
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