NP_006697.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
121,690 Da
NCBI Official Full Name
Homo sapiens transcription elongation regulator 1 (TCERG1), transcript variant 1, mRNA
NCBI Official Synonym Full Names
transcription elongation regulator 1
NCBI Protein Information
transcription elongation regulator 1; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD; TATA box-binding protein-associated factor 2S; co-activator of 150 kDa; transcription factor CA150
UniProt Protein Name
Transcription elongation regulator 1
UniProt Synonym Protein Names
TATA box-binding protein-associated factor 2S; Transcription factor CA150
UniProt Entry Name
TCRG1_HUMAN
NCBI Summary for TCERG1
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for TCERG1
TCERG1: Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Spliceosome; Transcription factor
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: nucleolus; nucleus; actin cytoskeleton
Molecular Function: protein binding; transcription coactivator activity
Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
Research Articles on TCERG1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-TCERG1 antibody
Pathways associated with anti-TCERG1 antibody
Diseases associated with anti-TCERG1 antibody
Organs/Tissues associated with anti-TCERG1 antibody
|