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anti-TIA-1 antibody :: Mouse anti-Human TIA-1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS370145
Unit / Price
5 Control Slides  /  $130 +1 FREE 8GB USB
3 ml (Prediluted)  /  $190 +1 FREE 8GB USB
0.1 mL (Concentrate)  /  $205 +1 FREE 8GB USB
7 ml (Prediluted)  /  $285 +1 FREE 8GB USB
15 ml (Prediluted)  /  $355 +1 FREE 8GB USB
0.5 mL (Concentrate)  /  $425 +1 FREE 8GB USB
1 mL (Concentrate)  /  $765 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TIA-1, Monoclonal Antibody

★Popular Item★
 Also Known As   


 Product Gene Name   

anti-TIA-1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    TIA-1
 Host    Mouse
 Species Reactivity    Human
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 Form/Format    TIA-1 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
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 Control    Tonsil, Spleen, Anaplastic Large Cell Lymphoma
 Localization    Cytoplasmic (Granular)
 Reactivity Note    Paraffin, Frozen
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 Preparation and Storage    Store at 2 to 8 degree C in the dark.
 Other Notes    Small volumes of anti-TIA-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TIA-1 antibody

   TIA-1 (T-cell intracytoplasmic antigen) is a 15 kDa cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. The expression of TIA-1 has been studied in Anaplastic Large Cell Lymphomas (ALCL), NK-cell Lymphomas, Peripheral T-cell Lymphomas, T-cell Lymphocytosis, B-cell Lymphomas and Lymphoblastic Leukemia, Hodgkin's, etc. Studies show that 60 to 70% of Anaplastic Large Cell Lymphomas react with TIA-1. TIA-1 reacts with most Large Granular Lymphocytic Leukemias, Hepatosplenic T-cell Lymphomas, intestinal T-cell Lymphomas, NK-like T-cell Lymphomas, NK-cell Lymphomas, nasal T/NK-cell Lymphomas, subcutaneous T-cell Lymphomas and Pulmonary Angiocentric Lymphomas of T- or NK-phenotype. All B-cell Lymphomas, Hodgkin's and Lymphoblastic Leukemias are negative for TIA-1.
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 Dilution Information of anti-TIA-1 antibody    anti-TIA-1 antibody Dilution Information image
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 Immunohistochemistry (IHC) of anti-TIA-1 antibody    anti-TIA-1 antibody Immunohistochemistry (IHC) (IHC) image
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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