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Mouse anti-Human TLR3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS605516 anti-TLR3 antibody
Unit / Price
0.1 mg  /  $630 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TLR3, Monoclonal Antibody

★Popular Item★
 Also Known As   

TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283 Antigen)

 Product Synonym Names    Anti -TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283 Antigen)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    9H184
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes human TLR3.
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
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 Immunogen    NS0 cells transfected with human TLR3 extracellular domain aa27-711; O15455.
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-TLR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TLR3 antibody

   Toll-like receptor 3 (TLR3) is a 103kDa (predicted, unglycosylated) type I transmembrane glycoprotein and member of the Toll-like receptor family. It is localized to the endoplasmic reticulum membrane and endosome, and is expressed at high levels in the placenta and pancreas. It is also detected in the dendritic subpopulation of leukocytes. Human TLR3 is synthesized as a precursor with a 23aa signal sequence, a 681aa luminal region, a 21aa transmembrane region, and a 179aa cytoplasmic region. The luminal region contains 23 canonical and two irregular leucine-rich repeats (LRR), 15 N-linked glycosylation sites, and a Toll/IL-1 receptor (TIR) domain (aa758-896). Human TLR3 shares 83% and 80% aa sequence identity with bovine and mouse TLR3, respectively. TLR3 is involved in the innate immune response to microbial agents.
 Product Categories/Family for anti-TLR3 antibody    Antibodies; Abs to Toll Like Receptors (TLR)
 Applications Tested/Suitable for anti-TLR3 antibody   

Western Blot (WB)

 Application Notes for anti-TLR3 antibody    Dilution: Western Blot: 2ug/ml
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NCBI/Uniprot data below describe general gene information for TLR3. It may not necessarily be applicable to this product.
 NCBI GI #    237871857
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 NCBI Official Full Name    TLR3
 Protein Family    Toll-like receptor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TLR3 antibodyPathways associated with anti-TLR3 antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with TLR3 and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-TLR3 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with TLR3 and Bone
 Connective Tissue Antibodies  >4 publications with TLR3 and Connective Tissue
 Heart Antibodies  >3 publications with TLR3 and Heart
 Muscle Antibodies  >3 publications with TLR3 and Muscle
 Brain Antibodies  >3 publications with TLR3 and Brain
 Vascular Antibodies  >2 publications with TLR3 and Vascular
 Embryonic Tissue Antibodies  >2 publications with TLR3 and Embryonic Tissue
 Ear Antibodies  >1 publications with TLR3 and Ear
 Kidney Antibodies  >1 publications with TLR3 and Kidney
 Umbilical Cord Antibodies  >1 publications with TLR3 and Umbilical Cord
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