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anti-TPH antibody :: Mouse TPH Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS533532 anti-TPH antibody
Unit / Price
1 mg  /  $255 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TPH, Monoclonal Antibody

 Also Known As   

TPH antibody (FITC)

 Product Synonym Names    Monoclonal TPH; Anti-TPH; Anti TPH; TPH; Anti Total Petroleum Hydrocarbons; Total Petroleum Hydrocarbons
 Product Gene Name   

anti-TPH antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    191060
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 Clonality    Monoclonal
 Clone Number    F12 3C8
 Host    Mouse
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 Form/Format    Supplied as a 0.2um filtered liquid in 20mM NaPO4, pH 7.2, with 150mM NaCl.
 Concentration    2.1 mg/ml (lot specific)
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 Biological Significance    Tryptophan hydroxylase (TPH) is an enzyme (EC involved in the synthesis of the neurotransmitter serotonin. TPH catalyzes the following chemical reaction: L-tryptophan + tetrahydrobiopterin + O2 5-Hydroxytryptophan + 4a-hydroxytetrahydrobiopterin. It employs one cofactor, iron.
 Tag/Conjugate    FITC
 Immunogen    TPH antibody (FITC) was raised in mouse using TPH as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-TPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TPH antibody

   TPH antibody (FITC)
 Product Categories/Family for anti-TPH antibody    Proteases, Inhibitors, & Enzymes; Conjugated Monoclonal Antibodies
 Applications Tested/Suitable for anti-TPH antibody   

User optimized

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NCBI/Uniprot data below describe general gene information for TPH. It may not necessarily be applicable to this product.
 NCBI GI #    531193
 NCBI Accession #    AAA67050.1 [Other Products]
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 UniProt Secondary Accession #    O95188; O95189; Q16736; Q3KPG8; D3DQX6 [Other Products]
 Molecular Weight    53,394 Da
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 NCBI Official Full Name    tryptophan hydroxylase
 UniProt Protein Name    Tryptophan 5-hydroxylase 1
 UniProt Synonym Protein Names   
Tryptophan 5-monooxygenase 1
 Protein Family    Tryptophan 5-hydroxylase
 UniProt Gene Name    TPH1 [Similar Products]
 UniProt Synonym Gene Names    TPH; TPRH; TRPH [Similar Products]
 UniProt Entry Name    TPH1_HUMAN
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 UniProt Comments for TPH    TPH1: an enzyme that is rate-limiting in the biosynthesis of serotonin. It catalyzes the biopterin dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Its expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells. Two alternatively spliced isoforms have been described.

Protein type: Oxidoreductase; Amino Acid Metabolism - tryptophan; EC

Chromosomal Location of Human Ortholog: 11p15.3-p14

Cellular Component: neuron projection; cytosol

Molecular Function: amino acid binding; tryptophan 5-monooxygenase activity; iron ion binding

Biological Process: circadian rhythm; indolalkylamine biosynthetic process; aromatic amino acid family metabolic process; negative regulation of ossification; positive regulation of fat cell differentiation; bone remodeling; serotonin biosynthetic process
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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