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anti-TUBB2A antibody :: Mouse TUBB2A / Tubulin Beta 2A Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS245516
Unit / Price
0.05 mg  /  $555 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TUBB2A / Tubulin Beta 2A, Monoclonal Antibody

 Also Known As   

Mouse Monoclonal [clone 2B2] (IgG2a,k) to Human TUBB2A / Tubulin Beta 2A

 Product Synonym Names    Anti-TUBB2A / Tubulin Beta 2A Antibody (clone 2B2) IHC-plus; TUBB2A; Class IIa beta-tubulin; DJ40E16.7; TUBB2; Tubulin beta-2A chain; Tubulin; beta 2; Tubulin; beta 2A; Tubulin; beta 2A class IIa; Beta-Tubulin; Tubulin beta-2 chain; Tubulin; beta polypeptide 2; Tubulin; beta polypeptide; Human TUBB2A; Tubulin Beta 2A
 Product Gene Name   

anti-TUBB2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 615763
 3D Structure    ModBase 3D Structure for Q13885
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 Clonality    Monoclonal
 Isotype    IgG2a,k
 Clone Number    2B2
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Protein A Purified
 Form/Format    PBS, pH 7.2
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 Target Species    Human
 Immunogen Description    TUBB2A (AAH01194, 1 a.a. ~ 446 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
 Immunogen Type    Recombinant protein
 Immunogen    TUBB2A / Tubulin Beta 2A antibody was raised against tUBB2A (AAH01194, 1 a.a. ~ 446 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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 Preparation and Storage    Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-TUBB2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-TUBB2A antibody    Family: Tubulin
 Applications Tested/Suitable for anti-TUBB2A antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

 Application Notes for anti-TUBB2A antibody    ELISA, IHC-P (5 ug/ml), WB
Usage: Western Blot (Cell lysate) - positive control PC-12. Western Blot (Cell lysate) - positive control Raw 264. Western Blot (Cell lysate) - positive control Jurkat. Western Blot (Cell lysate) - positive control NIH/3T3. Western Blot (Transfected lysate)...
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 Immunohistochemistry (IHC) of anti-TUBB2A antibody    Anti-TUBB2A antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-TUBB2A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TUBB2A antibody    Anti-TUBB2A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-TUBB2A antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-TUBB2A antibody    TUBB2A monoclonal antibody, clone 2B2. Western blot of TUBB2A expression in Jurkat.
anti-TUBB2A antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-TUBB2A antibody    TUBB2A monoclonal antibody, clone 2B2. Western blot of TUBB2A expression in NIH/3T3.
anti-TUBB2A antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for TUBB2A. It may not necessarily be applicable to this product.
 NCBI GI #    4507729
 NCBI GeneID    7280
 NCBI Accession #    NP_001060.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001069.2 [Other Products]
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 UniProt Primary Accession #    Q13885 [Other Products]
 UniProt Secondary Accession #    Q6FGZ8; Q8IWR2 [Other Products]
 UniProt Related Accession #    Q13885 [Other Products]
 Molecular Weight    49,907 Da
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 NCBI Official Full Name    tubulin beta-2A chain
 NCBI Official Synonym Full Names    tubulin, beta 2A class IIa
 NCBI Official Symbol    TUBB2A [Similar Products]
 NCBI Official Synonym Symbols   
TUBB; TUBB2; CDCBM5; dJ40E16.7
[Similar Products]
 NCBI Protein Information    tubulin beta-2A chain; class IIa beta-tubulin; tubulin beta class IIa; tubulin, beta polypeptide 2
 UniProt Protein Name    Tubulin beta-2A chain
 UniProt Synonym Protein Names   
Tubulin beta class IIa
 Protein Family    Tubulin
 UniProt Gene Name    TUBB2A [Similar Products]
 UniProt Synonym Gene Names    TUBB2 [Similar Products]
 UniProt Entry Name    TBB2A_HUMAN
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 NCBI Summary for TUBB2A    Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
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 UniProt Comments for TUBB2A    TUBB2A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: microtubule; cytoplasm; nucleus; vesicle

Molecular Function: GTPase activity; GTP binding; structural constituent of cytoskeleton

Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; transmembrane transport; microtubule-based process

Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5
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 Research Articles on TUBB2A    1. study associates mutations in TUBB2A with the spectrum of "tubulinopathy" phenotypes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TUBB2A antibodyPathways associated with anti-TUBB2A antibody
 Reference Product  PubMed Publications
 TUBA1A antibody  >2 publications with TUBB2A and TUBA1A
 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Orphan Transporters Pathway antibodies  Orphan Transporters Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
Diseases associated with anti-TUBB2A antibodyOrgans/Tissues associated with anti-TUBB2A antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with TUBB2A and Nervous System Diseases
 Lung Neoplasms Antibodies  >2 publications with TUBB2A and Lung Neoplasms
 Breast Neoplasms Antibodies  >2 publications with TUBB2A and Breast Neoplasms
 Disease Models, Animal Antibodies  >2 publications with TUBB2A and Disease Models, Animal
 Prostatic Diseases Antibodies  >1 publications with TUBB2A and Prostatic Diseases
 Atrophy Antibodies  >1 publications with TUBB2A and Atrophy
 Fatty Liver Antibodies  >1 publications with TUBB2A and Fatty Liver
 Necrosis Antibodies  >1 publications with TUBB2A and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with TUBB2A and Brain
 Lung Antibodies  >3 publications with TUBB2A and Lung
 Blood Antibodies  >2 publications with TUBB2A and Blood
 Ganglia Antibodies  >2 publications with TUBB2A and Ganglia
 Heart Antibodies  >1 publications with TUBB2A and Heart
 Prostate Antibodies  >1 publications with TUBB2A and Prostate
 Liver Antibodies  >1 publications with TUBB2A and Liver
 Ovary Antibodies  >1 publications with TUBB2A and Ovary
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