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anti-TPD52L1 antibody :: Mouse anti-Human Tumor Protein D52-Like 1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS607053 anti-TPD52L1 antibody
Unit / Price
0.1 mL  /  $510 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor Protein D52-Like 1 (TPD52L1), Monoclonal Antibody

 Also Known As   

Tumor Protein D52-Like 1 (TPD52L1, hD53, hD53L1)

 Product Synonym Names    Anti -Tumor Protein D52-Like 1 (TPD52L1, hD53, hD53L1)
 Product Gene Name   

anti-TPD52L1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 6; NC_000006.11 (125474879..125584644). Location: 6q22-q23
 OMIM    604069
 3D Structure    ModBase 3D Structure for Q16890
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 Clonality    Monoclonal
 Isotype    IgG2b,k
 Clone Number    7G43
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes human PEDF
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 0.08% sodium azide.
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 Immunogen    Recombinant GST-TPD52L1 protein
 Hybridoma    Sp2/0 myeloma cells with spleen cells from Balb/c mice.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-TPD52L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-TPD52L1 antibody

   D52-like (TPD52L1) protein is a member of D52 gene family and overexpressed in human breast carcinoma. This protein contains coiled-coil motif, which is responsible for homo- and heteromeric interaction, and may be regulators of cell proliferation and calcium-mediated signal transduction.
 Product Categories/Family for anti-TPD52L1 antibody    Antibodies; Abs to Cancer Markers
 Applications Tested/Suitable for anti-TPD52L1 antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-TPD52L1 antibody    Suitable for use in ELISA, immunohistochemistry, and Western Blot.
Dilution: Western Blot: 1:500-1:2000
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NCBI/Uniprot data below describe general gene information for TPD52L1. It may not necessarily be applicable to this product.
 NCBI GI #    56203491
 NCBI GeneID    7164
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 UniProt Primary Accession #    Q16890 [Other Products]
 UniProt Secondary Accession #    O43397; Q5TC99; Q5TDQ0; Q9BUQ6; Q9C054; A8K757; A8K772; A8MUD2; A8MUJ7; A8MW70 [Other Products]
 UniProt Related Accession #    Q15730; Q16890 [Other Products]
 Molecular Weight    22,449 Da [Similar Products]
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 NCBI Official Full Name    tumor protein D52-like 1
 NCBI Official Synonym Full Names    tumor protein D52-like 1
 NCBI Official Symbol    TPD52L1 [Similar Products]
 NCBI Official Synonym Symbols   
D53; hD53; MGC8556; TPD52L2
[Similar Products]
 NCBI Protein Information    tumor protein D53; OTTHUMP00000017133; OTTHUMP00000017134; OTTHUMP00000017135; OTTHUMP00000017136; OTTHUMP00000228908; OTTHUMP00000228944; OTTHUMP00000228945; OTTHUMP00000228946; OTTHUMP00000228947; OTTHUMP00000228948; tumor protein D52-like 2
 UniProt Protein Name    Tumor protein D53
 UniProt Synonym Protein Names   
Tumor protein D52-like 1
 Protein Family    Tumor protein
 UniProt Gene Name    TPD52L1 [Similar Products]
 UniProt Entry Name    TPD53_HUMAN
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 NCBI Summary for TPD52L1    This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq]
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 UniProt Comments for TPD52L1    TPD52L1: a member of the tumor protein D52 (TPD52) family. Contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. Interacts with the apoptosis signal-regulating kinase 1 (ASK1) and positively regulates ASK1-induced apoptosis. Multiple alternatively spliced transcript variants have been observed.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: perinuclear region of cytoplasm; cytoplasm

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: positive regulation of MAP kinase activity; positive regulation of JNK cascade; G2/M transition of mitotic cell cycle; regulation of caspase activity
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 Research Articles on TPD52L1    1. The results indicate that tumor protein D52-like 1 genes are not ubiquitously expressed in leukemic bone marrow in children, and that RNA sample parameters may influence measures of gene expression more than commonly appreciated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TPD52L1 antibodyPathways associated with anti-TPD52L1 antibody
 Reference Product  PubMed Publications
 TPD52 antibody  >7 publications with TPD52L1 and TPD52
 TPD52L2 antibody  >4 publications with TPD52L1 and TPD52L2
 MAL2 antibody  >2 publications with TPD52L1 and MAL2
 YWHAB antibody  >1 publications with TPD52L1 and YWHAB
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with anti-TPD52L1 antibodyOrgans/Tissues associated with anti-TPD52L1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with TPD52L1 and Neoplasms
 Breast Neoplasms Antibodies  >7 publications with TPD52L1 and Breast Neoplasms
 Carcinoma Antibodies  >6 publications with TPD52L1 and Carcinoma
 Leukemia Antibodies  >2 publications with TPD52L1 and Leukemia
 Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >1 publications with TPD52L1 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
 Neoplasm Metastasis Antibodies  >1 publications with TPD52L1 and Neoplasm Metastasis
 Leukemia, Myeloid Antibodies  >1 publications with TPD52L1 and Leukemia, Myeloid
 Leukemia, Myeloid, Acute Antibodies  >1 publications with TPD52L1 and Leukemia, Myeloid, Acute
 Neoplasms, Experimental Antibodies  >1 publications with TPD52L1 and Neoplasms, Experimental
 Gonadal Disorders Antibodies  >1 publications with TPD52L1 and Gonadal Disorders
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with TPD52L1 and Testis
 Bone Marrow Antibodies  >1 publications with TPD52L1 and Bone Marrow
 Bone Antibodies  >1 publications with TPD52L1 and Bone
 Skin Antibodies  >1 publications with TPD52L1 and Skin
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