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anti-tyrS antibody :: Mouse Tyrosyl-tRNA Synthetase Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS603750 anti-tyrS antibody
Unit / Price
0.1 mg  /  $565 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyrosyl-tRNA Synthetase (tyrS), Monoclonal Antibody

 Also Known As   

Tyrosyl-tRNA Synthetase (YARS, CMTDIC, TYRRS, YRS, YTS)

 Product Synonym Names    Anti -Tyrosyl-tRNA Synthetase (YARS, CMTDIC, TYRRS, YRS, YTS)
 Product Gene Name   

anti-tyrS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    NC_000913.2 (1713972..1715246, complement)
 3D Structure    ModBase 3D Structure for P0AGJ9
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    8C344
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes human Tyrosyl-tRNA Synthetase. Species Crossreactivity: Mouse and rat.
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
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 Immunogen    Partial sequence of recombinant full-length protein to human Tyrosyl-tRNA Synthetase
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-tyrS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-tyrS antibody    Antibodies; Abs to Enzymes, Synthetase
 Applications Tested/Suitable for anti-tyrS antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)

 Application Notes for anti-tyrS antibody    Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunocytochemistry.
Dilution: Flow Cytometry: 0.5-2ug/ml
Western Blot: 0.5-2ug/ml
Immunocytochemistry: 2-50ug/ml
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NCBI/Uniprot data below describe general gene information for tyrS. It may not necessarily be applicable to this product.
 NCBI GI #    16129595
 NCBI GeneID    948855
 NCBI Accession #    NP_416154.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_000913.2 [Other Products]
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 UniProt Primary Accession #    P0AGJ9 [Other Products]
 UniProt Secondary Accession #    P00951 [Other Products]
 Molecular Weight    47,527 Da [Similar Products]
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 NCBI Official Full Name    tyrosyl-tRNA synthetase
 NCBI Official Symbol    tyrS [Similar Products]
 NCBI Official Synonym Symbols   
ECK1633; JW1629
[Similar Products]
 NCBI Protein Information    tyrosyl-tRNA synthetase
 UniProt Protein Name    Tyrosyl-tRNA synthetase
 UniProt Synonym Protein Names   
Tyrosine--tRNA ligase
 Protein Family    Tyrosine--tRNA ligase
 UniProt Gene Name    tyrS [Similar Products]
 UniProt Entry Name    SYY_ECOLI
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 NCBI Summary for tyrS    Tyrosyl-tRNA synthetase (TyrRS) is a member of the family of aminoacyl-tRNA synthetases, which interpret the genetic code by covalently linking amino acids to their specific tRNA molecules. [More information is available at EcoCyc: EG11043].
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 UniProt Comments for tyrS    Function: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). HAMAP MF_02006

Catalytic activity: ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr). HAMAP MF_02006

Subunit structure: Homodimer. Ref.8

Subcellular location: Cytoplasm HAMAP MF_02006.

Sequence similarities: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.Contains 1 S4 RNA-binding domain.
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 Research Articles on tyrS    1. N-terminus verified by Edman degradation on mature peptide
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-tyrS antibody
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Mitochondrial TRNA Aminoacylation Pathway antibodies  Mitochondrial TRNA Aminoacylation Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
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