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anti-UBP1 antibody :: Mouse anti-Human UBP1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120311
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UBP1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human UBP1

 Product Synonym Names    Homo sapiens upstream binding protein 1 (LBP-1a) ; LBP1A; LBP1B; LBP-1B; LBP-1a; DKFZp686L1745
 Product Gene Name   

anti-UBP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609784
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    327C1a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-UBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-UBP1 antibody

   Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. [UniProtKB Function]
 Applications Tested/Suitable for anti-UBP1 antibody   

Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

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 Quality Control of anti-UBP1 antibody    Left: Western blot analysis of immunized recombinant protein, using anti-UBP1 monoclonal antibody.
anti-UBP1 antibody Quality Control image
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 Western Blot (WB) of anti-UBP1 antibody    Detection of human UBP1 by Western blot.

Samples: Whole cell lysate (25 ug) from HeLa cells. [Lot No. 327C1a-1]

Predicted molecular weight: 60 kDa
anti-UBP1 antibody Western Blot (WB) (WB) image
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 Immunocytochemistry (ICC) of anti-UBP1 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-UBP1 mAb. [Lot No. 327C1a-1]
anti-UBP1 antibody Immunocytochemistry (ICC) (ICC) image
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NCBI/Uniprot data below describe general gene information for UBP1. It may not necessarily be applicable to this product.
 NCBI GI #    189491629
 NCBI GeneID    7342
 NCBI Accession #    NP_055332.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_014517 [Other Products]
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 UniProt Secondary Accession #    Q68CT0; Q86Y57; Q9H8V0; Q9UD76; Q9UD78 [Other Products]
 UniProt Related Accession #    Q9NZI7 [Other Products]
 Molecular Weight    56,453 Da
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 NCBI Official Full Name    Homo sapiens upstream binding protein 1 (LBP-1a) (UBP1), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    upstream binding protein 1 (LBP-1a)
 NCBI Official Symbol    UBP1 [Similar Products]
 NCBI Official Synonym Symbols   
LBP1A; LBP1B; LBP-1B; LBP-1a
[Similar Products]
 NCBI Protein Information    upstream-binding protein 1; transcription factor LBP-1
 UniProt Protein Name    Upstream-binding protein 1
 UniProt Synonym Protein Names   
Transcription factor LBP-1
 Protein Family    UBP1-associated protein
 UniProt Gene Name    UBP1 [Similar Products]
 UniProt Entry Name    UBIP1_HUMAN
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 UniProt Comments for UBP1    UBP1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Belongs to the grh/CP2 family. CP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity; transcription corepressor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication; angiogenesis; negative regulation of transcription, DNA-dependent
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 Research Articles on UBP1    1. Data revealed that dimers composed of LBP-1a and LBP-1c were re-formed probably by a partner-exchange of LBP-1b-containing heterodimers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UBP1 antibodyDiseases associated with anti-UBP1 antibody
 Reference Product  PubMed Publications
 TFCP2L1 antibody  >4 publications with UBP1 and TFCP2L1
 YY1 antibody  >2 publications with UBP1 and YY1
 DPYD antibody  >1 publications with UBP1 and DPYD
 Disease Name  Pubmed Publications
 Fetal Growth Retardation Antibodies  >1 publications with UBP1 and Fetal Growth Retardation
 Fetal Death Antibodies  >1 publications with UBP1 and Fetal Death
 Necrosis Antibodies  >1 publications with UBP1 and Necrosis
Organs/Tissues associated with anti-UBP1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with UBP1 and Blood
 Placenta Antibodies  >4 publications with UBP1 and Placenta
 Embryonic Tissue Antibodies  >3 publications with UBP1 and Embryonic Tissue
 Bone Marrow Antibodies  >2 publications with UBP1 and Bone Marrow
 Lung Antibodies  >2 publications with UBP1 and Lung
 Bone Antibodies  >2 publications with UBP1 and Bone
 Connective Tissue Antibodies  >1 publications with UBP1 and Connective Tissue
 Liver Antibodies  >1 publications with UBP1 and Liver
 Skin Antibodies  >1 publications with UBP1 and Skin
 Kidney Antibodies  >1 publications with UBP1 and Kidney
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