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anti-VARS1 antibody :: Mouse anti-Human VARS1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120087
Quality Control
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

VARS1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human VARS1

 Product Synonym Names    Human G7a mRNA for valyl-tRNA synthetase.; G7a
 Product Gene Name   

anti-VARS1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    192150
 3D Structure    ModBase 3D Structure for P26640
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    VARSA7E6
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-VARS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-VARS1 antibody

   Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-VARS1 antibody   

Dot Blot (DB)

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 Quality Control of anti-VARS1 antibody    Left: Western blot analysis of immunized recombinant protein, using anti-VARS1 monoclonal antibody.
anti-VARS1 antibody Quality Control image
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NCBI/Uniprot data below describe general gene information for VARS1. It may not necessarily be applicable to this product.
 NCBI GI #    31544
 NCBI GeneID    7407
 NCBI Accession #    CAA41990.1 [Other Products]
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 UniProt Primary Accession #    P26640 [Other Products]
 UniProt Secondary Accession #    Q5JQ90; Q96E77; Q9UQM2; B0V1N1; B4DZ61 [Other Products]
 UniProt Related Accession #    P26640 [Other Products]
 Molecular Weight    33,795 Da
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 NCBI Official Full Name    Human G7a mRNA for valyl-tRNA synthetase
 NCBI Official Synonym Full Names    valyl-tRNA synthetase
 NCBI Official Symbol    VARS [Similar Products]
 NCBI Official Synonym Symbols   
G7A; VARS1; VARS2
[Similar Products]
 NCBI Protein Information    valine--tRNA ligase; protein G7a; valRS; valine tRNA ligase 1, cytoplasmic; valyl-tRNA synthetase 2
 UniProt Protein Name    Valine--tRNA ligase
 UniProt Synonym Protein Names   
Protein G7a; Valyl-tRNA synthetase; ValRS
 UniProt Gene Name    VARS [Similar Products]
 UniProt Entry Name    SYVC_HUMAN
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 NCBI Summary for VARS1    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
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 UniProt Comments for VARS1    VARS: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

Protein type: Ligase; Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.9

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: mitochondrion; cytosol

Molecular Function: valine-tRNA ligase activity; ATP binding

Biological Process: tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression; valyl-tRNA aminoacylation
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 Research Articles on VARS1    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VARS1 antibodyPathways associated with anti-VARS1 antibody
 Reference Product  PubMed Publications
 QARS antibody  >2 publications with VARS1 and QARS
 AARS antibody  >1 publications with VARS1 and AARS
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Cytosolic TRNA Aminoacylation Pathway antibodies  Cytosolic TRNA Aminoacylation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
Diseases associated with anti-VARS1 antibodyOrgans/Tissues associated with anti-VARS1 antibody
 Disease Name  Pubmed Publications
 Hemorrhage Antibodies  >5 publications with VARS1 and Hemorrhage
 Liver Diseases Antibodies  >4 publications with VARS1 and Liver Diseases
 Neurobehavioral Manifestations Antibodies  >3 publications with VARS1 and Neurobehavioral Manifestations
 Fatty Liver Antibodies  >3 publications with VARS1 and Fatty Liver
 Weight Loss Antibodies  >3 publications with VARS1 and Weight Loss
 Neoplasms, Experimental Antibodies  >3 publications with VARS1 and Neoplasms, Experimental
 Atrophy Antibodies  >2 publications with VARS1 and Atrophy
 Inflammation Antibodies  >2 publications with VARS1 and Inflammation
 Weight Gain Antibodies  >2 publications with VARS1 and Weight Gain
 Necrosis Antibodies  >2 publications with VARS1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >38 publications with VARS1 and Liver
 Blood Antibodies  >26 publications with VARS1 and Blood
 Intestine Antibodies  >13 publications with VARS1 and Intestine
 Vascular Antibodies  >10 publications with VARS1 and Vascular
 Kidney Antibodies  >5 publications with VARS1 and Kidney
 Brain Antibodies  >5 publications with VARS1 and Brain
 Muscle Antibodies  >4 publications with VARS1 and Muscle
 Eye Antibodies  >2 publications with VARS1 and Eye
 Heart Antibodies  >2 publications with VARS1 and Heart
 Thyroid Antibodies  >2 publications with VARS1 and Thyroid
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