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anti-VEGF121 antibody :: Mouse anti-Human Vascular Endothelial Growth Factor 121 (VEGF121) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2059837 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-VEGF121 antibody
Unit / Price
0.01 mg  /  $205 +1 FREE 8GB USB
0.02 mg  /  $235 +1 FREE 8GB USB
0.05 mg  /  $370 +1 FREE 8GB USB
0.1 mg  /  $505 +1 FREE 8GB USB
0.2 mg  /  $705 +1 FREE 8GB USB
1 mg  /  $1,715 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vascular Endothelial Growth Factor 121 (VEGF121), Monoclonal Antibody

 Also Known As   

APC/CY7-Linked Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121)

 Product Gene Name   

anti-VEGF121 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor 121 (VEGF121) Clone #C2 (MBS2090565)
APC-CY7 Conjugated Antibody: Vascular Endothelial Growth Factor 121 (VEGF121) (MBS2059837)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M32977 mRNA
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 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Human
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 Concentration    500ug/ml (lot specific)
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 Immunogen    Pro28~Arg137
 Conjugation    APC-Cy7
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2090565
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 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-VEGF121 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-VEGF121 antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for VEGF121. It may not necessarily be applicable to this product.
 NCBI GI #    6631029
 NCBI GeneID    7422
 NCBI Accession #    AAF19659.1 [Other Products]
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 UniProt Secondary Accession #    O60720; O75875; Q074Z4; Q16889; B5BU86; H0Y2S8; H0Y407; H0Y414; H0Y462; H0Y8N2; H3BLW7 [Other Products]
 UniProt Related Accession #    P15692 [Other Products]
 Molecular Weight    34,406 Da
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 NCBI Official Full Name    vascular endothelial growth factor isoform 121
 NCBI Official Synonym Full Names    vascular endothelial growth factor A
 NCBI Official Symbol    VEGFA [Similar Products]
 NCBI Official Synonym Symbols   
VPF; VEGF; MVCD1
[Similar Products]
 NCBI Protein Information    vascular endothelial growth factor A
 UniProt Protein Name    Vascular endothelial growth factor A
 UniProt Synonym Protein Names   
Vascular permeability factor; VPF
 UniProt Gene Name    VEGFA [Similar Products]
 UniProt Synonym Gene Names    VEGF; VEGF-A; VPF [Similar Products]
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 NCBI Summary for VEGF121    This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
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 UniProt Comments for VEGF121    Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
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 Research Articles on VEGF121    1. The positive rates of VEGF expression was 93.75% (45/48) in the condylomata acuminata tissues, and 94.44%(17/18) in the controls, respectively. High expressions of NDRG1 and VEGF influenced both the occurrence and development of CA.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VEGF121 antibodyPathways associated with anti-VEGF121 antibody
 Reference Product  PubMed Publications
 HIF1A antibody  >603 publications with VEGF121 and HIF1A
 KDR antibody  >289 publications with VEGF121 and KDR
 FLT1 antibody  >196 publications with VEGF121 and FLT1
 TGFB1 antibody  >166 publications with VEGF121 and TGFB1
 MMP9 antibody  >124 publications with VEGF121 and MMP9
 SRC antibody  >69 publications with VEGF121 and SRC
 NRP1 antibody  >59 publications with VEGF121 and NRP1
 VWF antibody  >52 publications with VEGF121 and VWF
 IGF1 antibody  >31 publications with VEGF121 and IGF1
 PGF antibody  >27 publications with VEGF121 and PGF
 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Cellular Response To Hypoxia Pathway antibodies  Cellular Response To Hypoxia Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-VEGF121 antibodyOrgans/Tissues associated with anti-VEGF121 antibody
 Disease Name  Pubmed Publications
 Neovascularization, Pathologic Antibodies  >2123 publications with VEGF121 and Neovascularization, Pathologic
 Retinal Diseases Antibodies  >1697 publications with VEGF121 and Retinal Diseases
 Neoplasm Metastasis Antibodies  >544 publications with VEGF121 and Neoplasm Metastasis
 Diabetic Retinopathy Antibodies  >525 publications with VEGF121 and Diabetic Retinopathy
 Inflammation Antibodies  >525 publications with VEGF121 and Inflammation
 Lung Diseases Antibodies  >448 publications with VEGF121 and Lung Diseases
 Diabetes Complications Antibodies  >448 publications with VEGF121 and Diabetes Complications
 Macular Edema Antibodies  >423 publications with VEGF121 and Macular Edema
 Heart Diseases Antibodies  >298 publications with VEGF121 and Heart Diseases
 Head and Neck Neoplasms Antibodies  >287 publications with VEGF121 and Head and Neck Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >8789 publications with VEGF121 and Vascular
 Blood Antibodies  >3287 publications with VEGF121 and Blood
 Eye Antibodies  >1654 publications with VEGF121 and Eye
 Lung Antibodies  >582 publications with VEGF121 and Lung
 Bone Antibodies  >582 publications with VEGF121 and Bone
 Muscle Antibodies  >487 publications with VEGF121 and Muscle
 Embryonic Tissue Antibodies  >437 publications with VEGF121 and Embryonic Tissue
 Heart Antibodies  >402 publications with VEGF121 and Heart
 Liver Antibodies  >386 publications with VEGF121 and Liver
 Kidney Antibodies  >371 publications with VEGF121 and Kidney
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