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anti-VEGFC antibody :: Mouse anti-Mouse Vascular Endothelial Growth Factor C (VEGFC) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090552 anti-VEGFC antibody
Unit / Price
0.01 mg  /  $100 +1 FREE 8GB USB
0.02 mg  /  $105 +1 FREE 8GB USB
0.05 mg  /  $135 +1 FREE 8GB USB
0.1 mg  /  $165 +1 FREE 8GB USB
0.2 mg  /  $210 +1 FREE 8GB USB
1 mg  /  $465 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vascular Endothelial Growth Factor C (VEGFC), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC)

 Product Synonym Names    VEGF-C; Flt4-L; VRPL; Vascular Endothelial Growth Factor-Related Protein
 Product Gene Name   

anti-VEGFC antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor C (VEGFC) (MBS2090552)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor C (VEGFC) (MBS2090552)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor C (VEGFC) (MBS2090552)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor C (VEGFC) (MBS2090552)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
 Matching Pairs    Unconjugated Antibody: Vascular Endothelial Growth Factor C (VEGFC) (MBS2090552)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P97953
 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Mouse
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 Specificity    The antibody is a mouse monoclonal antibody raised against VEGFC. It has been selected for its ability to recognize VEGFC in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific affinity chromatography followed by Protein A affinity chromatography
 Form/Format    Liquid
 Concentration    1mg/mL (lot specific)
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 Buffer Formulation    PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-VEGFC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-VEGFC antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-VEGFC antibody    Western blotting: 0.2-2ug/mL;1:500-5000
Immunohistochemistry: 5-20ug/mL;1:50-200
Immunocytochemistry: 5-20ug/mL;1:50-200
Optimal working dilutions must be determined by end user.
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NCBI/Uniprot data below describe general gene information for VEGFC. It may not necessarily be applicable to this product.
 NCBI GI #    6678565
 NCBI GeneID    22341
 NCBI Accession #    NP_033532.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009506.2 [Other Products]
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 UniProt Primary Accession #    P97953 [Other Products]
 UniProt Secondary Accession #    Q543R6; C6F5S8; C6F5S9; C6F5T0 [Other Products]
 UniProt Related Accession #    P97953 [Other Products]
 Molecular Weight    6,405 Da
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 NCBI Official Full Name    vascular endothelial growth factor C
 NCBI Official Synonym Full Names    vascular endothelial growth factor C
 NCBI Official Symbol    Vegfc [Similar Products]
 NCBI Official Synonym Symbols   
VEGF-C; AW228853
[Similar Products]
 NCBI Protein Information    vascular endothelial growth factor C
 UniProt Protein Name    Vascular endothelial growth factor C
 UniProt Synonym Protein Names   
Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP
 Protein Family    Vascular endothelial growth factor
 UniProt Gene Name    Vegfc [Similar Products]
 UniProt Synonym Gene Names    VEGF-C; Flt4-L; VRP [Similar Products]
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 UniProt Comments for VEGFC    VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family.

Protein type: Cell cycle regulation; Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8|8 B1.3

Cellular Component: extracellular region; extracellular space; membrane

Molecular Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding

Biological Process: angiogenesis; cell differentiation; induction of positive chemotaxis; morphogenesis of embryonic epithelium; multicellular organism development; negative regulation of blood pressure; negative regulation of cell proliferation; organ morphogenesis; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of cell-matrix adhesion; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of neuroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein amino acid autophosphorylation; positive regulation of protein secretion; regulation of vascular endothelial growth factor receptor signaling pathway; response to hypoxia; vascular endothelial growth factor receptor signaling pathway
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 Research Articles on VEGFC    1. lymphangiogenesis is regulated by two distinct proteolytic mechanisms of ligand activation: one in which VEGFC activation by ADAMTS3 and CCBE1 spatially and temporally patterns developing lymphatics, and one in which VEGFD activation by a distinct proteolytic mechanism may be stimulated during inflammatory lymphatic growth
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VEGFC antibodyPathways associated with anti-VEGFC antibody
 Reference Product  PubMed Publications
 Vegfa antibody  >200 publications with VEGFC and Vegfa
 Flt4 antibody  >76 publications with VEGFC and Flt4
 Kdr antibody  >46 publications with VEGFC and Kdr
 Flt1 antibody  >21 publications with VEGFC and Flt1
 Pdgfrb antibody  >9 publications with VEGFC and Pdgfrb
 Figf antibody  >7 publications with VEGFC and Figf
 Pdgfra antibody  >2 publications with VEGFC and Pdgfra
 Igf2 antibody  >1 publications with VEGFC and Igf2
 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion-PI3K-Akt-mTOR-signaling Pathway antibodies  Focal Adhesion-PI3K-Akt-mTOR-signaling Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-VEGFC antibodyOrgans/Tissues associated with anti-VEGFC antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >661 publications with VEGFC and Neoplasm Metastasis
 Carcinoma Antibodies  >641 publications with VEGFC and Carcinoma
 Adenocarcinoma Antibodies  >218 publications with VEGFC and Adenocarcinoma
 Breast Neoplasms Antibodies  >168 publications with VEGFC and Breast Neoplasms
 Neoplasm Invasiveness Antibodies  >162 publications with VEGFC and Neoplasm Invasiveness
 Lung Diseases Antibodies  >159 publications with VEGFC and Lung Diseases
 Inflammation Antibodies  >158 publications with VEGFC and Inflammation
 Lung Neoplasms Antibodies  >157 publications with VEGFC and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >131 publications with VEGFC and Neoplasms, Experimental
 Recurrence Antibodies  >82 publications with VEGFC and Recurrence
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >655 publications with VEGFC and Blood
 Lung Antibodies  >226 publications with VEGFC and Lung
 Skin Antibodies  >142 publications with VEGFC and Skin
 Embryonic Tissue Antibodies  >92 publications with VEGFC and Embryonic Tissue
 Eye Antibodies  >65 publications with VEGFC and Eye
 Bone Marrow Antibodies  >55 publications with VEGFC and Bone Marrow
 Brain Antibodies  >36 publications with VEGFC and Brain
 Tongue Antibodies  >27 publications with VEGFC and Tongue
 Spleen Antibodies  >7 publications with VEGFC and Spleen
 Mammary Gland Antibodies  >5 publications with VEGFC and Mammary Gland
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