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anti-YEATS4 antibody :: Mouse anti-Human YEATS4 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120135
Quality Control
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

YEATS4, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human YEATS4

 Product Synonym Names    Homo sapiens YEATS domain containing 4 (YEATS4); YAF9; GAS41;NUBI-1; 4930573H17Rik; B230215M10Rik
 Product Gene Name   

anti-YEATS4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602116
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    YEATB1A8
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-YEATS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-YEATS4 antibody

   The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-YEATS4 antibody   

Dot Blot (DB)

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 Quality Control of anti-YEATS4 antibody    Left: Western blot analysis of immunized recombinant protein, using anti-YEATS4 monoclonal antibody.
anti-YEATS4 antibody Quality Control image
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NCBI/Uniprot data below describe general gene information for YEATS4. It may not necessarily be applicable to this product.
 NCBI GI #    665821255
 NCBI GeneID    8089
 NCBI Accession #    NP_006521.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006530 [Other Products]
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 UniProt Secondary Accession #    Q9NQD0 [Other Products]
 UniProt Related Accession #    O95619 [Other Products]
 Molecular Weight    26,499 Da
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 NCBI Official Full Name    Homo sapiens YEATS domain containing 4 (YEATS4), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    YEATS domain containing 4
 NCBI Official Symbol    YEATS4 [Similar Products]
 NCBI Official Synonym Symbols   
YAF9; GAS41; NUBI-1; 4930573H17Rik; B230215M10Rik
[Similar Products]
 NCBI Protein Information    YEATS domain-containing protein 4; NuMA binding protein 1; glioma-amplified sequence 41; glioma-amplified sequence-41; nuBI1; nuMA-binding protein 1
 UniProt Protein Name    YEATS domain-containing protein 4
 UniProt Synonym Protein Names   
Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1
 Protein Family    YEATS domain-containing protein
 UniProt Gene Name    YEATS4 [Similar Products]
 UniProt Entry Name    YETS4_HUMAN
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 NCBI Summary for YEATS4    The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
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 UniProt Comments for YEATS4    YEATS4: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 12q13-q15

Cellular Component: nucleoplasm; NuA4 histone acetyltransferase complex; nuclear matrix; cytoplasm; nucleolus

Molecular Function: protein C-terminus binding; protein binding; DNA binding; structural constituent of cytoskeleton; transcription factor activity

Biological Process: mitosis; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of growth; positive regulation of transcription, DNA-dependent
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 Research Articles on YEATS4    1. Findings reveal YEATS4 as a candidate oncogene amplified in NSCLC, and a novel mechanism contributing to NSCLC pathogenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-YEATS4 antibodyPathways associated with anti-YEATS4 antibody
 Reference Product  PubMed Publications
 NUMA1 antibody  >2 publications with YEATS4 and NUMA1
 KAT5 antibody  >1 publications with YEATS4 and KAT5
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 HATs Acetylate Histones Pathway antibodies  HATs Acetylate Histones Pathway Diagram
Diseases associated with anti-YEATS4 antibodyOrgans/Tissues associated with anti-YEATS4 antibody
 Disease Name  Pubmed Publications
 Liposarcoma Antibodies  >6 publications with YEATS4 and Liposarcoma
 Breast Neoplasms Antibodies  >2 publications with YEATS4 and Breast Neoplasms
 Carcinoma Antibodies  >1 publications with YEATS4 and Carcinoma
 Inflammation Antibodies  >1 publications with YEATS4 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with YEATS4 and Blood
 Brain Antibodies  >3 publications with YEATS4 and Brain
 Lung Antibodies  >1 publications with YEATS4 and Lung
 Connective Tissue Antibodies  >1 publications with YEATS4 and Connective Tissue
 Mammary Gland Antibodies  >1 publications with YEATS4 and Mammary Gland
 Embryonic Tissue Antibodies  >1 publications with YEATS4 and Embryonic Tissue
 Testis Antibodies  >1 publications with YEATS4 and Testis
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